Nayler G L, Firmin D N, Longmore D B
J Comput Assist Tomogr. 1986 Sep-Oct;10(5):715-22. doi: 10.1097/00004728-198609000-00001.
A technique for measuring blood flow by whole body nuclear magnetic resonance is described. This method uses imaging gradient profiles that combine even echo rephasing with a field echo sequence to overcome the problem of signal loss from flowing blood. The flow velocity component in any desired direction may be measured by appropriate gradient profile modifications, producing velocity dependent phase shifts that can be displayed by phase mapping. The sequence allows for fast repetition so that flow information may be acquired rapidly from many points in the cardiac cycle and has been used in this mode to observe and measure blood flow in the heart chambers and great vessels. Flow measurements in the femoral artery were also carried out using the same technique; these were compared with similar measurements obtained by Doppler ultrasound. The technique can readily be applied using standard imaging equipment and should prove useful in the clinical assessment of many diseases of the cardiovascular system.
本文描述了一种通过全身核磁共振测量血流的技术。该方法使用成像梯度轮廓，将偶数回波重聚与场回波序列相结合，以克服流动血液信号丢失的问题。通过适当修改梯度轮廓，可以测量任何所需方向上的流速分量，产生与速度相关的相移，这些相移可以通过相位映射显示。该序列允许快速重复，以便可以在心动周期的多个点快速获取血流信息，并已在这种模式下用于观察和测量心腔和大血管中的血流。还使用相同技术对股动脉进行了血流测量；并将这些测量结果与通过多普勒超声获得的类似测量结果进行了比较。该技术可以很容易地使用标准成像设备应用，并且应该在许多心血管系统疾病的临床评估中证明是有用的。
