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采用射频烧灼术联合外用5-氟尿嘧啶治疗累及唇角的白癜风复色

Re-pigmentation of Vitiligo Involving Angle of Lip Using Radiofrequency Cautery and Topical 5-Fluorouracil.

作者信息

Hassanandani Trashita, Kar Bikash Ranjan

机构信息

Department of Dermatology, IMS and SUM Hospital, Bhubaneswar, Odisha, India.

出版信息

J Cutan Aesthet Surg. 2021 Oct-Dec;14(4):456-457. doi: 10.4103/JCAS.JCAS_187_20.

DOI:10.4103/JCAS.JCAS_187_20
PMID:35283607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8906275/
Abstract

Vitiligo involving the angle of lip is a therapeutically challenging site because of the small and delicate area, high mobility, and lack of hair follicles. Dermabrasion combined with topical 5-fluorouracil cream has shown promising results in various studies involving different sites. Here we present a novel technique of using radiofrequency cautery for abrasion of epidermis followed by application of 5-fluorouracil cream. This technique has the advantage of being simple, easy, cost-effective with less downtime. A single session can yield excellent pigmentation in small areas such as the angle of lip.

摘要

累及唇角的白癜风是一个治疗上具有挑战性的部位,因为该区域面积小且精细、活动度高且缺乏毛囊。在涉及不同部位的各种研究中,皮肤磨削术联合外用5-氟尿嘧啶乳膏已显示出有前景的结果。在此,我们介绍一种新技术,即使用射频烧灼进行表皮磨削,随后涂抹5-氟尿嘧啶乳膏。该技术具有操作简单、容易、成本效益高且停机时间短的优点。单次治疗就能在唇角等小面积区域产生出色的色素沉着。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda0/8906275/6f020b05d6de/JCAS-14-456-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda0/8906275/6f020b05d6de/JCAS-14-456-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fda0/8906275/6f020b05d6de/JCAS-14-456-g001.jpg

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Re-pigmentation of Vitiligo Involving Angle of Lip Using Radiofrequency Cautery and Topical 5-Fluorouracil.采用射频烧灼术联合外用5-氟尿嘧啶治疗累及唇角的白癜风复色
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引用本文的文献

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J Cutan Aesthet Surg. 2022 Oct-Dec;15(4):355-362. doi: 10.4103/JCAS.JCAS_10_22.

本文引用的文献

1
Suction Blister Epidermal Grafting for Vitiligo Involving Angles of Lip: Experience of 112 Patients.唇部角部白癜风的负压吸疱表皮移植术:112例患者的经验
J Cutan Aesthet Surg. 2018 Jan-Mar;11(1):13-19. doi: 10.4103/JCAS.JCAS_111_15.
2
The Prevalence of Vitiligo: A Meta-Analysis.白癜风的患病率:一项荟萃分析。
PLoS One. 2016 Sep 27;11(9):e0163806. doi: 10.1371/journal.pone.0163806. eCollection 2016.
3
Combination of microdermabrasion and 5-fluorouracil to induce repigmentation in vitiligo: an observational study.微磨削术联合 5-氟尿嘧啶诱导白癜风复色:一项观察性研究。
Dermatol Surg. 2011 Dec;37(12):1763-6. doi: 10.1111/j.1524-4725.2011.02127.x. Epub 2011 Aug 11.
4
Effect of one session of ER:YAG laser ablation plus topical 5Fluorouracil on the outcome of short-term NB-UVB phototherapy in the treatment of non-segmental vitiligo: a left-right comparative study.单次 Er:YAG 激光消融联合外用 5-氟尿嘧啶对非节段型白癜风短期窄谱中波紫外线光疗疗效的影响:一项左右对照研究
Photodermatol Photoimmunol Photomed. 2008 Dec;24(6):322-9. doi: 10.1111/j.1600-0781.2008.00385.x.
5
Topically administered fluorouracil in vitiligo.外用氟尿嘧啶治疗白癜风。
Arch Dermatol. 1983 Sep;119(9):722-7.