Eftekhari Moghadam Ali Reza, Fazelinejad Zahra, Nashibi Roohangiz, Pour Mohsen Bouri
Department of Anatomical Sciences, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Department of Radiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Adv Biomed Res. 2022 Jan 31;11:10. doi: 10.4103/abr.abr_33_21. eCollection 2022.
This research intended to investigate the characteristics of COVID-19, accurately evaluate radiological findings, and compare it with laboratory evidence of coronavirus.
A retrospective study of 120 consecutive cases with a mean age of 55.9 ± 15.82 years and laboratory-confirmed COVID-19 pneumonia was performed. On admission, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels were tested. Computed tomography (CT) findings and scored pulmonary involvement were evaluated.
An elevated level of CRP and mildly raised ESR was seen in all patients. ESR showed a meaningful difference between both genders ( < 0.05). Ninety-four (78.3%) patients showed peripheral pulmonary lesions and 119 patients had ground-glass opacity (99.2%), 110 (92.4%) had consolidation, and 9 patients (7.5%) had linear opacities. Of 120 cases, 25 (20%) had bronchial changes, 25 (20%) had air bronchogram, 11 (9.2%) had bronchial distortion, and 2 had mediastinal lymphadenopathy. The CT scores in males and females were 17.41 ± 4.86 and 14.65 ± 4.96, respectively with a significant difference between both genders ( = 0.001). CT score difference was significant between both genders ( = 0.01). The largest lung lesion diameter in both sexes (male: 46.0725.75 and female: 57.9131.14) showed a meaningful difference. CRP ( = 0.10; < 0.05) and ESR ( = 0.15; < 0.05) were correlated with the CT scores.
the results indicated that the infection involved lung parenchyma and interstitium. CRP and ESR levels were correlated with lung lesions and showed positive performance in predicting severity and disease monitoring.
本研究旨在调查新型冠状病毒肺炎（COVID-19）的特征，准确评估影像学表现，并将其与冠状病毒的实验室证据进行比较。
对120例连续病例进行回顾性研究，这些病例的平均年龄为55.9±15.82岁，均经实验室确诊为COVID-19肺炎。入院时检测C反应蛋白（CRP）和红细胞沉降率（ESR）水平。评估计算机断层扫描（CT）表现及肺部受累评分。
所有患者CRP水平均升高，ESR轻度升高。ESR在两性之间存在显著差异（<0.05）。94例（78.3%）患者表现为外周肺部病变，119例患者有磨玻璃影（99.2%），110例（92.4%）有实变，9例（7.5%）有线状影。120例病例中，25例（20%）有支气管改变，25例（20%）有空气支气管征，11例（9.2%）有支气管扭曲，2例有纵隔淋巴结肿大。男性和女性的CT评分分别为17.41±4.86和14.65±4.96，两性之间存在显著差异（=0.001）。CT评分在两性之间差异显著（=0.01）。两性最大肺病变直径（男性：46.07±25.75，女性：57.91±31.14）存在显著差异。CRP（=0.10；<0.05）和ESR（=0.15；<0.05）与CT评分相关。
结果表明感染累及肺实质和间质。CRP和ESR水平与肺部病变相关，在预测病情严重程度和疾病监测方面表现出阳性作用。
