Instituto de Ciencias, Universidad Nacional de General Sarmiento (UNGS), J. M. Gutiérrez 1150, (B1613GSX) Los Polvorines; Prov. de Buenos Aires, Buenos Aires, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Environ Sci Pollut Res Int. 2022 Jul;29(35):53382-53394. doi: 10.1007/s11356-022-19561-9. Epub 2022 Mar 14.
The objective of this work was to evaluate thermal paper (TP) tickets used in Argentina as a potential source of bisphenol A (BPA) that could impact humans and the environment. BPA in TP was measured by HPLC ranging from 11.1 to 30.5 mg BPAg. In order to estimate the impact on humans, dermal BPA estimated daily intake was calculated as being 79.3 ± 19.5 μgd for workers and 1.6 ± 0.4 μgd for the general population. To evaluate TP's impact on the environment, BPA migration from TP to water and soil was studied. In the case of water, 99.6% of the BPA tickets content migrated in 30 h, while 78.0% moved into the soil in 96 h. BPA degradation kinetics in soil and water were also carried out; while in soil 61.9% of BPA degraded in 120 h, no degradation was observed up to 120 h in tap or river water.Additionally, ecotoxicological effects of BPA on the earthworm Eisenia andrei, a representative terrestrial indicator, were studied performing bioassays on lethality, avoidance, and reproductive and enzymatic activity. BPA showed to be very toxic to E. andrei (LC value in contact paper test of 17 μgcm, 95% confidence interval 6-46 μgcm, 24 h exposure) and also caused an increase of total cocoons for earthworms exposed to 10 and 50 mg BPA kg soil. Evasion response was observed at a concentration of 50 mg BPA kg soil, while no effect was observed on cholinesterases, carboxylesterases, and glutathione S-transferases activities (1, 10, and 50 mg BPA kg soil). Finally, a simple BPA degradation technology using water peroxide and radish (Raphanus sativus) tissue as catalyst was explored as a simple and domestic potential treatment to avoid BPA migration to the environment.
本研究旨在评估阿根廷热敏纸（TP）票作为一种可能影响人类和环境的双酚 A（BPA）潜在来源的可能性。通过高效液相色谱法（HPLC）测量 TP 中的 BPA，其浓度范围为 11.1 至 30.5mg BPAg。为了评估对人类的影响，通过计算得出工人的皮肤 BPA 日摄入量估计值为 79.3 ± 19.5 μgd，一般人群为 1.6 ± 0.4 μgd。为了评估 TP 对环境的影响，研究了 TP 中 BPA 向水和土壤的迁移情况。在水的情况下，99.6%的 BPA 票含量在 30 小时内迁移，而 78.0%在 96 小时内迁移到土壤中。还进行了 BPA 在土壤和水中的降解动力学研究；在土壤中，61.9%的 BPA 在 120 小时内降解，而在自来水中或河水中，在 120 小时内未观察到降解。此外，还研究了 BPA 对代表性陆生指示生物赤子爱胜蚓（Eisenia andrei）的生态毒理学效应，通过致死率、回避和生殖及酶活性生物测定进行了实验。结果表明，BPA 对 E. andrei 具有很强的毒性（接触纸测试中 LC 值为 17μgcm，95%置信区间为 6-46μgcm，24 小时暴露），同时还导致暴露于 10 和 50mg BPA kg 土壤中的蚯蚓总茧数量增加。在 50mg BPA kg 土壤的浓度下观察到回避反应，而对胆碱酯酶、羧酸酯酶和谷胱甘肽 S-转移酶活性（1、10 和 50mg BPA kg 土壤）没有影响。最后，探索了一种使用过氧化氢和萝卜（Raphanus sativus）组织作为催化剂的简单 BPA 降解技术，作为一种简单的家庭潜在处理方法，以避免 BPA 向环境迁移。
