Assunção-Costa Lindemberg, Ribeiro Pinto Charleston, Ferreira Fernandes Machado Juliana, Gomes Valli Cleidenete, Portela Fernandes de Souza Luís Eugênio, Dean Franklin Bryony
Universidade Federal da Bahia.
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J Public Health Res. 2022 Mar 14;11(2):2623. doi: 10.4081/jphr.2022.2623.
Medication errors are frequent and have a high economic and social impact and is critical to know their severity. A variety of tools exist to measure and classify the harms associated with medication errors, but few are internationally validated.
It was decided to validate a method proposed by Dean and Barber for assessment of the potential severity of medication administration errors. A number of thirty health care professionals (doctors, nurses and pharmacists) from Brazil will receive an invitation to take part by scoring 50 cases of medication errors gathered from an original UK study regarding their potential harm to the patient on scale 0 to 10. Sixteen cases with known actual harm outcomes will be used to assess the validity of their scoring. By looking at 10 errors (out of the 50 cases) scored twice, reliability shall be assessed; and potential sources of variability in scoring will be evaluated depending on the severity of each of error case, the occasion when the scores were given, the scorer, their profession, and interactions among these variables. Generalizability theory will be used for analysing data. Expected impact of the study for public health: This study was submitted to the evaluation of the Research Ethics Committee of the Complexo Hospitalar Universitário Professor Edgard Santos and approved under no. 3.102.570/2019. This is the first validation of this method for use in Brazil, and will allow researchers to conduct more standardised evaluations of interventions to reduce the impact of medication errors.
用药错误屡见不鲜，具有很高的经济和社会影响，了解其严重程度至关重要。有多种工具可用于衡量和分类与用药错误相关的危害，但很少有经过国际验证的。
决定对迪恩和巴伯提出的一种评估用药错误潜在严重程度的方法进行验证。来自巴西的30名医疗保健专业人员（医生、护士和药剂师）将收到邀请，对从英国一项原始研究中收集的50例用药错误案例进行评分，评估其对患者的潜在危害程度，评分范围为0至10分。将使用16例已知实际危害结果的案例来评估他们评分的有效性。通过查看50例案例中的10例错误（这些错误被评分两次）来评估可靠性；并将根据每个错误案例的严重程度、评分时间、评分者、其职业以及这些变量之间的相互作用来评估评分中潜在的变异性来源。将使用概化理论来分析数据。该研究对公共卫生的预期影响：本研究已提交给埃德加德·桑托斯大学医院综合研究伦理委员会评估，并于2019年第3.102.570号批准。这是该方法在巴西首次进行验证，将使研究人员能够对减少用药错误影响的干预措施进行更标准化的评估。
