Pilgramm M, Schäfer A, Schumann K
Laryngol Rhinol Otol (Stuttg). 1986 Jul;65(7):381-3.
A study was carried out on 60 patients who had suffered an acute acoustic trauma. The aim of the study was to examine the effect of using naphtidrofurylhydrogen oxalate (Dusodril Pi. i.v. or Dusodril ret.) as an adjunctive measure alongside dextran-40 infusions (Thomaedex 40). After spontaneous remissions had been largely excluded, the patients were randomly assigned to two therapy groups. Very similar results were obtained in the naphtidrofurylhydrogen oxalate group and in the control group (30 patients each), showing that the use of this drug as an adjunctive therapeutic measure in the treatment of high-frequency hearing loss or alleviated tinnitus does not produce a significant improvement of results.
对60例急性声创伤患者进行了一项研究。该研究的目的是检验使用草酸萘呋胺酯（杜索德里尔静脉注射剂或杜索德里尔缓释剂）作为右旋糖酐-40输注（托马德克斯40）的辅助措施的效果。在基本排除自发缓解后，将患者随机分为两个治疗组。草酸萘呋胺酯组和对照组（每组30例患者）得到了非常相似的结果，表明在治疗高频听力损失或缓解耳鸣时使用这种药物作为辅助治疗措施并没有显著改善疗效。
