[Efficacy of naftidrofurylhydrogenoxalate (Dusodril) as adjunctive therapy of patients with acute acoustic trauma. A controlled double-blind study].

A study was carried out on 60 patients who had suffered an acute acoustic trauma. The aim of the study was to examine the effect of using naphtidrofurylhydrogen oxalate (Dusodril Pi. i.v. or Dusodril ret.) as an adjunctive measure alongside dextran-40 infusions (Thomaedex 40). After spontaneous remissions had been largely excluded, the patients were randomly assigned to two therapy groups. Very similar results were obtained in the naphtidrofurylhydrogen oxalate group and in the control group (30 patients each), showing that the use of this drug as an adjunctive therapeutic measure in the treatment of high-frequency hearing loss or alleviated tinnitus does not produce a significant improvement of results.