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生殖道微生物群的微生态平衡与失调及其与生殖功能关系的观点。

Perspective on the relationship between reproductive tract microbiota eubiosis and dysbiosis and reproductive function.

作者信息

Hashem Nesrein M, Gonzalez-Bulnes Antonio

机构信息

Department of Animal and Fish Production, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria 21545, Egypt.

Departamento de Produccion y Sanidad Animal, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, C/ Tirant lo Blanc, 7, Alfara del Patriarca, 46115 Valencia, Spain.

出版信息

Reprod Fertil Dev. 2022 Apr;34(7):531-539. doi: 10.1071/RD21252.

DOI:10.1071/RD21252
PMID:35287791
Abstract

The role played by microbiota is attracting growing attention within the scientific and medical community, in both human and animal fields, in the last years. Most of the studies have been focused on the intestinal microbiome, whilst little attention has been paid to other systems, like the reproductive tract of both females and males. However, there is a growing body of information showing the interplay between reproductive tract dysbiosis, due to the action of pathogens and/or unhealthy lifestyle, and reproductive disease and disorders in many mammalian species. The present review aims to summarise current knowledge on the biodiversity of the microbiota of the reproductive tract, and the possible relationships between eubiosis or dysbiosis and reproductive health and function in both females and males.

摘要

近年来,微生物群所起的作用在科学和医学界正受到越来越多的关注,涉及人类和动物领域。大多数研究都集中在肠道微生物组,而对其他系统,如雌性和雄性的生殖道关注较少。然而,越来越多的信息表明,由于病原体的作用和/或不健康的生活方式导致的生殖道生态失调与许多哺乳动物物种的生殖疾病和紊乱之间存在相互作用。本综述旨在总结关于生殖道微生物群生物多样性的现有知识,以及共生或失调与雌性和雄性生殖健康及功能之间可能存在的关系。

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