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坏血病仍存在于儿童中:一例报告。

Scurvy still exists in children: A case report.

出版信息

Tunis Med. 2021;99(11):1093-1096.

PMID:35288913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9390125/
Abstract

Scurvy is one of the oldest diseases known to mankind. Although rare lately, the clinical suspicion arises in front of a precarious situation or deficient nutrition and food restriction secondary to a psychiatric condition, even in patients with non-specific complaints. We report the observation of a 6 -year- old boy, followed for autism since the age of 3 years and who was admitted for limping, hemorrhagic syndrome, arthritis and weakness. The diagnosis of child abuse was initially suspected but clinical and radiological abnormalities seen were characteristic of scurvy. Vitamin C level was undetectable. The child had an unbalanced diet.A favorable outcome was rapidly obtained following supplementation. Scurvy is rare, but it should be mentioned among children with psychiatric disorders, presenting with musculoskeletal manifestations or hemorrhagic syndrome. It is essential to prevent it by systematic dietary supplementation of vitamin C in children with eating difficulties.

摘要

坏血病是人类已知的最古老的疾病之一。尽管最近很少见,但在面临不稳定的情况或因精神疾病而导致的营养和食物限制时,临床医生会怀疑坏血病,即使是在有非特异性投诉的患者中也是如此。我们报告了一名 6 岁男孩的观察结果,他从 3 岁起就因自闭症接受治疗,因跛行、出血综合征、关节炎和虚弱而入院。最初怀疑是儿童虐待,但临床和影像学异常具有坏血病的特征。维生素 C 水平无法检测到。孩子的饮食不均衡。补充治疗后迅速取得了良好的效果。坏血病很少见,但对于有精神障碍、表现出肌肉骨骼表现或出血综合征的儿童,应提及坏血病。通过对有饮食困难的儿童进行系统的维生素 C 饮食补充来预防坏血病是很重要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d93/9390125/8bb70a797e7e/image3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d93/9390125/4533f735f5d4/image1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d93/9390125/f7d1acc1acf1/image2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d93/9390125/8bb70a797e7e/image3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d93/9390125/4533f735f5d4/image1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d93/9390125/f7d1acc1acf1/image2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d93/9390125/8bb70a797e7e/image3.jpg

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本文引用的文献

1
Scurvy presenting with limp and weakness: a case report.以跛行和虚弱为表现的坏血病:一例报告
BMC Pediatr. 2019 Jul 6;19(1):228. doi: 10.1186/s12887-019-1605-5.
2
Brief Report: Scurvy as a Manifestation of Food Selectivity in Children with Autism.简短报告:坏血病作为自闭症儿童食物选择性的一种表现
J Autism Dev Disord. 2016 Apr;46(4):1464-70. doi: 10.1007/s10803-015-2660-x.
3
Scurvy in pediatric age group - A disease often forgotten?小儿年龄组中的坏血病——一种常被遗忘的疾病?
J Clin Orthop Trauma. 2015 Jun;6(2):101-7. doi: 10.1016/j.jcot.2014.12.003. Epub 2015 Jan 5.
4
Magnetic resonance imaging appearance of scurvy with gelatinous bone marrow transformation.坏血病伴胶状骨髓转变的磁共振成像表现。
Skeletal Radiol. 2012 Mar;41(3):357-60. doi: 10.1007/s00256-011-1350-9. Epub 2012 Jan 6.
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Infantile scurvy: two case reports.婴儿坏血病:两例报告
Int J Pediatr. 2010;2010:717518. doi: 10.1155/2010/717518. Epub 2010 Sep 29.
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Scurvy: reemergence of nutritional deficiencies.坏血病:营养缺乏症的再度出现。
Can Fam Physician. 2008 Oct;54(10):1403-6.
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Scurvy: MRI appearances.坏血病:磁共振成像表现
Rheumatology (Oxford). 2008 Jul;47(7):1109. doi: 10.1093/rheumatology/ken160. Epub 2008 May 22.
8
Scurvy: a disease almost forgotten.坏血病:一种几乎被遗忘的疾病。
Int J Dermatol. 2006 Aug;45(8):909-13. doi: 10.1111/j.1365-4632.2006.02844.x.
9
Scurvy in pediatric patients: a review of 28 cases.小儿坏血病:28例病例回顾
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