Montero C G, Martinez A J
Neurology. 1986 Sep;36(9):1149-54. doi: 10.1212/wnl.36.9.1149.
We reviewed the clinical histories, operative results, and neuropathologic findings of 23 consecutive patients who had heart transplants. Prolonged preoperative hypotension and failure of cerebral autoregulation of blood flow, followed by postoperative elevation of blood pressure beyond the limits of cerebral autoregulation, may account for the high incidence of neurologic complications (70%); 60% were vascular. Immunosuppressive therapy may have been responsible for the high incidence (20%) of opportunistic intracranial infections. Lymphoproliferative disorders occurred in three patients (13%).
我们回顾了连续23例心脏移植患者的临床病史、手术结果和神经病理学发现。术前长时间低血压和脑血流自动调节功能衰竭，随后术后血压升高超出脑自动调节范围，可能是神经并发症高发（70%）的原因；60%为血管性并发症。免疫抑制治疗可能是机会性颅内感染高发（20%）的原因。三名患者（13%）发生了淋巴增生性疾病。
