Epstein J B, Stevenson-Moore P
Oral Surg Oral Med Oral Pathol. 1986 Aug;62(2):145-8. doi: 10.1016/0030-4220(86)90035-6.
Benzydamine hydrochloride rinse reduced pain associated with radiation mucositis when it was used during the course of radiation therapy. Fewer patients using benzydamine rinse required systemic analgesics. All patients using benzydamine tolerated the rinse well and continued with regular rinsing throughout the course of radiation therapy. Benzydamine hydrochloride is currently undergoing clinical trials in the United States for application for approval from the Food and Drug Administration.
在放射治疗过程中使用盐酸苄达明漱口水可减轻与放射性口腔黏膜炎相关的疼痛。使用苄达明漱口水的患者中，需要使用全身性镇痛药的人数较少。所有使用苄达明的患者对漱口水耐受性良好，并在整个放射治疗过程中持续定期漱口。目前，盐酸苄达明正在美国进行临床试验，以申请获得美国食品药品监督管理局的批准。
