Department of Animal Science, Texas A&M University, College Station, TX, 77843, USA.
Ajinomoto Co., Inc, 1-15-1 Kyobashi, Chuoku, Tokyo, 104-8315, Japan.
Amino Acids. 2022 Jul;54(7):1055-1068. doi: 10.1007/s00726-022-03147-3. Epub 2022 Mar 16.
This study was conducted to test the hypothesis that increasing dietary content of glutamate through addition of monosodium glutamate (MSG) enhances milk production by lactating sows and the growth of their offspring. Thirty multiparous sows (Landrace × Large White) were assigned randomly into one of three dietary groups: control (a corn- and soybean meal-based diet), the basal diet + 1% MSG, and the basal diet + 2% MSG. Diets were made isonitrogenous by the addition of appropriate amounts of L-alanine. Lactating sows had free access to drinking water and were fed twice daily their respective diets. The number of live-born piglets was standardized to 9 per sow at day 0 of lactation (the day of farrowing). On days 3, 15, and 29 of lactation, body weight and milk consumption of piglets were measured, and blood samples obtained from sows and piglets at 2 h and 1 h after feeding, respectively. Feed intake of sows did not differ (P > 0.05) among the three groups of sows. Concentrations of aspartate, glutamine, citrulline, arginine, tryptophan, proline, branched-chain amino acids, and glutamate were greater (P < 0.05) in the plasma of MSG-supplemented sows and their piglets than for controls. When compared with the control, dietary supplementation with 1-2% MSG increased (P < 0.05): concentrations of many free amino acids (including glutamate plus glutamine) and all protein-bound amino acids in milk; the milk intake of piglets by 14-25%; and daily weight gains of piglets by 23-44%. These results indicate that dietary supplementation with 1-2% MSG to lactating sows enhances milk production to support the growth of sow-reared piglets.
通过添加味精（MSG）增加饮食中的谷氨酸含量，可以提高哺乳期母猪的产奶量及其后代的生长速度。
将 30 头经产母猪（长白猪×大白猪）随机分为三组：对照组（基于玉米和豆粕的日粮）、基础日粮+1%MSG 组和基础日粮+2%MSG 组。通过添加适量的 L-丙氨酸使日粮保持等氮水平。哺乳期母猪可以自由饮水，并每天分两次喂养各自的日粮。在哺乳期第 0 天（分娩当天），将每头母猪的活产仔猪数标准化为 9 头。在哺乳期第 3、15 和 29 天，测量仔猪的体重和采食量，并分别在母猪和仔猪进食后 2 小时和 1 小时采集血液样本。三组母猪的采食量没有差异（P＞0.05）。在添加 MSG 的母猪及其仔猪的血浆中，天冬氨酸、谷氨酰胺、瓜氨酸、精氨酸、色氨酸、脯氨酸、支链氨基酸和谷氨酸的浓度均较高（P＜0.05）。与对照组相比，日粮中添加 1%-2%的 MSG 增加了（P＜0.05）：许多游离氨基酸（包括谷氨酸加谷氨酰胺）和所有结合蛋白氨基酸在乳中的浓度；仔猪的采食量增加了 14%-25%；仔猪的日增重增加了 23%-44%。这些结果表明，哺乳期母猪日粮中添加 1%-2%的 MSG 可提高产奶量，以支持母猪所哺育仔猪的生长。
