Health Research Union/Clinic NEOLAB, Tbilisi, Georgia.
TEPHINET, Tbilisi, Georgia.
J Med Screen. 2022 Jun;29(2):134-136. doi: 10.1177/09691413221086497. Epub 2022 Mar 16.
Georgia has a high prevalence of hepatitis C virus (HCV) infection. In 2015 a national HCV elimination program was launched providing free access to screening and treatment. To achieve elimination, innovative approaches to increase screening coverage and linkage to care are needed. This study estimates feasibility, acceptability, and outcomes of the door-to-door pilot HCV testing program in three cities.
Households were approached by system random sampling and all members were invited for study participation. Researchers used a detailed guide for conducting door-to-door testing and served as case navigators to link anti-HCV-positive individuals to care.
Testing acceptance rate was high. In total 4804 individuals were tested and 48 (1.0%) were HCV positive. Among the entire sample of newly and previously tested individuals, overall HCV antibody prevalence was 3.6%. Through case navigation, of 48 newly identified and 26 previously identified anti-HCV-positive individuals, 42 (87.5%) and 17 (65.4%), respectively, were successfully linked to care.
Door-to-door HCV testing has potential to increase testing uptake. Such community-based approaches not only improve testing, but can also serve to increase linkage to care, which is important in achieving the goal of HCV elimination. The study provides a model for high prevalence countries aiming to eliminate hepatitis C.
格鲁吉亚丙型肝炎病毒 (HCV) 感染率很高。2015 年,该国启动了一项国家 HCV 消除计划,为筛查和治疗提供免费服务。为了实现消除目标,需要采取创新方法来提高筛查覆盖率并将其与治疗联系起来。本研究评估了在三个城市开展挨家挨户 HCV 试点检测计划的可行性、可接受性和结果。
通过系统随机抽样接近家庭,邀请所有成员参与研究。研究人员使用详细的指南进行挨家挨户检测,并充当病例导航员,将抗 HCV 阳性个体与治疗联系起来。
检测接受率很高。共检测了 4804 人,有 48 人(1.0%)HCV 阳性。在新检测和以前检测过的个体的整个样本中,丙型肝炎病毒抗体总流行率为 3.6%。通过病例导航,新发现的 48 名和以前发现的 26 名抗 HCV 阳性个体中,分别有 42 名(87.5%)和 17 名(65.4%)成功联系到治疗。
挨家挨户 HCV 检测有可能提高检测率。这种基于社区的方法不仅可以改善检测,还可以帮助与治疗联系起来,这对于实现 HCV 消除目标非常重要。该研究为旨在消除丙型肝炎的高流行国家提供了一种模式。