Trooskin Stacey B, Poceta Joanna, Towey Caitlin M, Yolken Annajane, Rose Jennifer S, Luqman Najia L, Preston Ta-Wanda L, Chan Philip A, Beckwith Curt, Feller Sophie C, Lee Hwajin, Nunn Amy S
Division of Infectious Diseases, Drexel University College of Medicine, Philadelphia, PA, USA.
J Gen Intern Med. 2015 Jul;30(7):950-7. doi: 10.1007/s11606-015-3209-6. Epub 2015 Feb 14.
Many of the five million Americans chronically infected with hepatitis C (HCV) are unaware of their infection and are not in care.
We implemented and evaluated HCV screening and linkage-to-care interventions in a community setting.
We developed a comprehensive, community-based HCV screening and linkage-to-care program in a medically underserved neighborhood with high rates of HCV infection in Philadelphia, Pennsylvania. We provided patient navigation services to enroll uninsured patients in insurance programs, facilitate referrals from primary care physicians and link patients to an HCV infectious disease specialist with intention to treat and cure.
Philadelphia residents were recruited through street outreach.
We measured anti-HCV seroprevalence and diagnosis, linkage and retention in care outcomes for chronically infected patients.
We screened 1,301 participants for HCV; anti-HCV seroprevalence was 3.9 % and 2.8% of all patients were chronically infected. Half of chronically infected patients were newly diagnosed; the remaining patients were aware of infection but not in care. We provided confirmatory RNA testing and results, assisted patients with attaining insurance and linked most chronically infected patients to a primary care provider. The biggest barrier to retaining patients in care was obtaining referrals for subspecialty providers; however, we obtained referrals for 64% of chronically infected participants and have retained most in subspecialty HCV care. Several have commenced treatment.
Non-clinical screening programs with patient navigator services are an effective means to diagnose, link, retain and re-engage patients in HCV care. Eliminating referral requirements for subspecialty care might further enhance retention in care for patients chronically infected with HCV.
五百万慢性丙型肝炎(HCV)感染的美国人中,许多人并未意识到自己已被感染,也未接受治疗。
我们在社区环境中实施并评估了丙型肝炎病毒筛查及治疗衔接干预措施。
我们在宾夕法尼亚州费城一个医疗服务不足、丙型肝炎病毒感染率高的社区,制定了一个全面的、基于社区的丙型肝炎病毒筛查及治疗衔接项目。我们提供患者导航服务,让未参保患者加入保险计划,促进初级保健医生的转诊,并将患者与丙型肝炎传染病专科医生联系起来,以便进行治疗和治愈。
通过街头宣传招募费城居民。
我们测量了慢性感染患者的抗丙型肝炎病毒血清流行率、诊断情况、治疗衔接及治疗持续情况。
我们对1301名参与者进行了丙型肝炎病毒筛查;抗丙型肝炎病毒血清流行率为3.9%,所有患者中有2.8%为慢性感染。一半的慢性感染患者是新诊断出来的;其余患者已知感染但未接受治疗。我们提供了确诊的RNA检测及结果,协助患者获得保险,并将大多数慢性感染患者与初级保健提供者联系起来。让患者持续接受治疗的最大障碍是获得专科提供者的转诊;然而,我们为64%的慢性感染参与者获得了转诊,并让大多数人持续接受丙型肝炎专科治疗。有几个人已经开始治疗。
带有患者导航服务的非临床筛查项目是诊断、衔接、留住和重新让患者参与丙型肝炎治疗的有效手段。消除专科护理的转诊要求可能会进一步提高慢性丙型肝炎感染患者的治疗持续率。