Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
The Chester M. Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Chronobiol Int. 2022 Jul;39(7):984-990. doi: 10.1080/07420528.2022.2053703. Epub 2022 Mar 16.
In the present study, we examined associations between circadian preference and psychiatric symptoms among 1,796 pregnant women from Lima, Peru. One quarter were classified as evening types. Compared to morning types, evening type pregnant women had increased odds of generalized anxiety (OR = 1.44; 95%CI: 1.12-1.86) and posttraumatic stress disorder (OR = 1.38; 95%CI: 1.07-1.78). Although there was a positive trend, evening chronotype was not significantly associated with elevated odds of depression (OR = 1.23; 95%CI: 0.94-1.61). Future studies are warranted to help understand the underlying behavioral, biological, and genetic pathways of these associations. Assessing circadian preference may help clinicians identify pregnant women at risk for psychiatric symptoms.
在本研究中，我们研究了秘鲁利马的 1796 名孕妇的昼夜节律偏好与精神症状之间的关联。其中四分之一被归类为“晚型”。与“早型”相比，“晚型”孕妇出现广泛性焦虑（OR=1.44；95%CI：1.12-1.86）和创伤后应激障碍（OR=1.38；95%CI：1.07-1.78）的几率增加。尽管存在正相关趋势，但昼夜节律类型与抑郁（OR=1.23；95%CI：0.94-1.61）的几率升高无关。需要进一步研究来帮助理解这些关联的潜在行为、生物学和遗传途径。评估昼夜节律偏好可能有助于临床医生识别有精神症状风险的孕妇。
