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土耳其一家三级眼科中心小儿眼部化学烧伤十年经验。

Ten Years of Pediatric Ocular Chemical Burn Experience in a Tertiary Eye Care Center in Turkey.

机构信息

Department of Ophthalmology, Ege University Medical Faculty Hospital, Izmir, Turkey.

出版信息

Eye Contact Lens. 2022 Apr 1;48(4):175-179. doi: 10.1097/ICL.0000000000000858.

Abstract

OBJECTIVES

To report 10 years of pediatric ocular chemical burn experience in a tertiary eye care center in Turkey.

METHODS

Thirty-three patients aged 18 years and younger who presented with ocular chemical burn between 2011 and 2021 were enrolled. Demographic data and clinical characteristics of patients were reviewed. Limbal stem cell deficiency (LSCD) stage was assessed according to LSCD working group's staging system. The initial and final best-corrected visual acuities were recorded.

RESULTS

The mean age was 10.4±5.5 (0.25-18) years with an F/M ratio of 12/21. Eleven (33.3%) of the patients were injured with acid and 5 (15.1%) with alkaline. The most common causative agent was nail polish remover (n=7, 21.2%), followed by cologne (n=5, 15.1%) and hand sanitizer (n=4, 12.1%). The severity of burn was ≥grade 4 in 20 patients (60.6%). Chemical injury resulted in LSCD in 18 patients (54.5%). Surgery was performed (LSCD ≥Stage 2 B) in 13 patients (39.3%); limbal stem cell transplantation (LSCT) (n=11), staged amniotic membrane transplantation, and symblepharon release (n=2). Penetrating keratoplasty after LSCT was performed in three of 11 patients. The mean follow-up time was 31.9±28.6 months (6-102.33) after the surgery.

CONCLUSIONS

In pediatric population, accurate diagnosis and management of ocular chemical burns are challenging. Although the severity of burn and consequently LSCD rate seems to be high in children, comparative studies in a larger population are still needed.

摘要

目的

报告土耳其一家三级眼科中心 10 年来儿科眼部化学烧伤的经验。

方法

纳入 2011 年至 2021 年间因眼部化学烧伤就诊的 33 名 18 岁以下患者。回顾患者的人口统计学数据和临床特征。根据 Limbal Stem Cell Deficiency (LSCD) 工作组的分期系统评估 Limbal Stem Cell Deficiency (LSCD) 分期。记录初始和最终最佳矫正视力。

结果

平均年龄为 10.4±5.5 岁(0.25-18 岁),男女比例为 12/21。11 名(33.3%)患者为酸性烧伤,5 名(15.1%)为碱性烧伤。最常见的致伤剂是指甲油去除剂(n=7,21.2%),其次是古龙水(n=5,15.1%)和洗手液(n=4,12.1%)。20 名患者(60.6%)烧伤程度≥4 级。化学伤导致 18 名患者(54.5%)出现 LSCD。13 名患者(39.3%)进行了手术(LSCD≥Stage 2B);行 Limbal Stem Cell Transplantation (LSCT)(n=11)、分期羊膜移植和睑球粘连松解术(n=2)。11 名患者中的 3 名在 LSCT 后行穿透性角膜移植术。术后平均随访时间为 31.9±28.6 个月(6-102.33 个月)。

结论

在儿科人群中,眼部化学烧伤的准确诊断和治疗具有挑战性。尽管儿童烧伤的严重程度和由此导致的 LSCD 发生率似乎较高,但仍需要在更大的人群中进行比较研究。

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