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埃及上埃及地区白内障超声乳化术后干眼症的发病率

The Incidence of Post Phacoemulsification Surgery Induced Dry Eye Disease in Upper Egypt.

作者信息

Hamed Mohamed Ateto, Aldghaimy Ahmed Hasan, Mohamed Nouran Saleh, Amer Ahmed Ali

机构信息

Ophthalmology Department, Luxor University, Luxor, Egypt.

Ophthalmology Department, South Valley University, Qena, Egypt.

出版信息

Clin Ophthalmol. 2022 Mar 9;16:705-713. doi: 10.2147/OPTH.S358866. eCollection 2022.

DOI:10.2147/OPTH.S358866
PMID:35300035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8921793/
Abstract

BACKGROUND

Dry eye is described as a multifactorial disorder of the tear film that occurs due to excessive tear evaporation or tears insufficiency, and so leads to ocular discomfort sensation and ocular tissue damage with time.

OBJECTIVE

To assess the incidence of dry eye disease after uncomplicated phacoemulsification surgery in patients with no pre-existed dry eye.

PATIENTS AND METHODS

This hospital-based cross-sectional study was conducted to assess the incidence of dry eye at 100 eyes of 100 patients who underwent uncomplicated phacoemulsification surgery, with age more than 45 years old. It is measured by dry eye tests Schirmer 1 and tear break up time.

RESULTS

This study showed that 22% of the patients who underwent uncomplicated phacoemulsification surgery suffered from dry eye with significant results at 1st week post-operative that improved over time.

CONCLUSION

There was a statistically significant drop in the results of the Schirmer test 1 and TBUT post phacoemulsification surgery, but with no clinical significance as they still at the normal range. The tear film assessment results at the 1st week post-operative were out of the normal range with TBUT and were borderline with ST1 in 22% of the patients. These results improved over time to return to the normal values within 12 weeks postoperatively.

摘要

背景

干眼症被描述为一种泪膜的多因素疾病,其发生是由于泪液过度蒸发或泪液不足,随着时间的推移会导致眼部不适感和眼组织损伤。

目的

评估无干眼症病史的患者在进行单纯白内障超声乳化手术后干眼症的发生率。

患者与方法

本基于医院的横断面研究旨在评估100例年龄超过45岁且接受单纯白内障超声乳化手术患者的100只眼中干眼症的发生率。通过Schirmer 1试验和泪膜破裂时间来测量。

结果

本研究表明,接受单纯白内障超声乳化手术的患者中有22%患有干眼症,术后第1周结果显著,随着时间推移有所改善。

结论

白内障超声乳化手术后Schirmer试验1和泪膜破裂时间的结果有统计学意义的下降,但由于仍在正常范围内,故无临床意义。术后第1周泪膜评估结果中,22%的患者泪膜破裂时间超出正常范围,Schirmer试验1处于临界状态。这些结果随着时间推移有所改善,术后12周内恢复到正常数值。

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本文引用的文献

1
Mechanisms and management of dry eye in cataract surgery patients.白内障手术患者干眼的机制与管理
Curr Opin Ophthalmol. 2016 Jan;27(1):24-30. doi: 10.1097/ICU.0000000000000227.
2
The course of dry eye after phacoemulsification surgery.白内障超声乳化吸除术后干眼的病程
BMC Ophthalmol. 2015 Jun 30;15:68. doi: 10.1186/s12886-015-0058-3.
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[Recent advances in dry eye: etiology, pathogenesis and management].[干眼的最新进展:病因、发病机制及治疗]
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Incidence and pattern of dry eye after cataract surgery.白内障手术后干眼症的发生率和模式。
PLoS One. 2013 Nov 12;8(11):e78657. doi: 10.1371/journal.pone.0078657. eCollection 2013.
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The effect of preservative-free HP-Guar on dry eye after phacoemulsification: a flow cytometric study.无防腐剂 HP-Guar 对白内障超声乳化术后干眼的影响:流式细胞术研究。
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Architecture and distribution of human corneal nerves.人眼角膜神经的结构与分布。
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Dry eye after cataract surgery and associated intraoperative risk factors.白内障手术后的干眼及相关术中危险因素。
Korean J Ophthalmol. 2009 Jun;23(2):65-73. doi: 10.3341/kjo.2009.23.2.65. Epub 2009 Jun 9.
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Sensitivity change in cornea and tear layer due to incision difference on cataract surgery with either manual small-incision cataract surgery or phacoemulsification.白内障手术采用手法小切口白内障手术或超声乳化手术时,因切口差异导致的角膜和泪膜敏感性变化。
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Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery.白内障手术后患者干眼疾病的调查及致病因素分析
Cornea. 2007 Oct;26(9 Suppl 1):S16-20. doi: 10.1097/ICO.0b013e31812f67ca.
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Dry eye symptoms following cataract surgery.白内障手术后的干眼症状。
Insight. 2007 Jan-Mar;32(1):14-21; quiz 22-3.