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白内障手术后干眼症的发生率和模式。

Incidence and pattern of dry eye after cataract surgery.

机构信息

Department of Ophthalmology, Chulalongkorn University, Bangkok, Thailand.

出版信息

PLoS One. 2013 Nov 12;8(11):e78657. doi: 10.1371/journal.pone.0078657. eCollection 2013.

Abstract

PURPOSE

To evaluate the incidence and severity pattern of dry eye after phacoemulsification.

SETTING

King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

DESIGN

Prospective descriptive study.

METHODS

Samples were collected from ninety-two uncomplicated cataract patients who were 18 years old or older. Dry eye incidence and pattern were analyzed at days 0, 7, 30 and 90 after phacoemulsification using (1) Ocular Surface Disease Index (OSDI) questionnaire, (2) tear break up time (TBUT), (3) Oxford ocular surface staining system, and (4) Schirmer I test without anesthesia.

RESULTS

Seven days after phacoemulsification, the incidence of dry eye was 9.8% (95% confidence interval; 3.6-16.0%). The severity of dry eye peaked seven days post-phacoemulsification and was measured by OSDI questionnaire and all three clinical tests. Within thirty days and 3 months post-surgery, both the symptoms and signs showed rapid and gradual improvements, respectively. However, dry eye post-phacoemulsification was not significantly associated with sex and systemic hypertension (P = 0.26, 0.17 and 0.73, respectively).

CONCLUSIONS

The incidence of dry eye after phacoemulsification was 9.8%. Symptoms and signs of dry eye occurred as early as seven days post-phacoemulsification and the severity pattern improved over time. We recommend that ophthalmologists should evaluate patients both before and after phacoemulsification to prevent further damage to the ocular surface and able to manage the patient promptly and effectively so the patient will not have a poor quality of life and vision due to dry eye syndrome.

摘要

目的

评估白内障超声乳化术后干眼的发生率和严重程度模式。

地点

泰国曼谷朱拉隆功纪念医院。

设计

前瞻性描述性研究。

方法

从 92 名年龄在 18 岁或以上的无并发症白内障患者中采集样本。术后 0、7、30 和 90 天,使用(1)眼表面疾病指数(OSDI)问卷、(2)泪膜破裂时间(TBUT)、(3)牛津眼表面染色系统和(4)无麻醉的 Schirmer I 试验,分析干眼的发生率和模式。

结果

白内障超声乳化术后 7 天,干眼发生率为 9.8%(95%置信区间:3.6-16.0%)。术后 7 天,干眼的严重程度达到高峰,并通过 OSDI 问卷和所有三种临床检查进行测量。术后 30 天和 3 个月内,症状和体征分别迅速改善和逐渐改善。然而,白内障超声乳化术后干眼与性别和高血压无显著相关性(P=0.26、0.17 和 0.73)。

结论

白内障超声乳化术后干眼的发生率为 9.8%。术后 7 天即可出现干眼症状和体征,严重程度随时间逐渐改善。我们建议眼科医生在白内障超声乳化术前和术后都对患者进行评估,以防止眼表进一步受损,并能够及时有效地对患者进行治疗,避免因干眼综合征导致患者生活质量和视力下降。

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