Scupham R, Gilbert E F, Wilde J, Wiedrich T A
Arch Pathol Lab Med. 1986 Sep;110(9):818-21.
We performed immunoperoxidase studies in 29 cases of rhabdomyosarcoma from the Intergroup Rhabdomyosarcoma Study I using antisera against actin, myosin, myoglobin, alpha-actinin, and tropomyosin. Although each of these antisera reacted with some of the tumors, none reacted with all of the tumors, and some tumors showed no reactivity. Antimyosin reacted with more tumors than any of the others, while antiactin and antimyoglobin were about equally sensitive. Antitropomyosin and anti-alpha-actinin reacted with few of the tumors. The better-differentiated tumors were more likely to react compared with the poorly differentiated tumors.
我们使用抗肌动蛋白、肌球蛋白、肌红蛋白、α-辅肌动蛋白和原肌球蛋白的抗血清，对横纹肌肉瘤研究I组的29例横纹肌肉瘤进行了免疫过氧化物酶研究。虽然这些抗血清中的每一种都与一些肿瘤发生反应，但没有一种与所有肿瘤都发生反应，而且有些肿瘤没有反应。抗肌球蛋白与比其他任何抗血清都更多的肿瘤发生反应，而抗肌动蛋白和抗肌红蛋白的敏感性大致相同。抗原肌球蛋白和抗α-辅肌动蛋白与很少的肿瘤发生反应。与低分化肿瘤相比，高分化肿瘤更有可能发生反应。
