Centre de Référence des Maladies Rares du Calcium et du Phosphore, Service de Néphrologie Rhumatologie Dermatologie Pédiatriques, Filières Santé Maladies Rares OSCAR, ORKID et ERKNet, Hôpital Femme Mère Enfant, 59 Boulevard Pinel, Bron 69677 CEDEX, France; INSERM U1033, LYOS, Prévention des Maladies Osseuses, Lyon, France; Faculté de Médecine Lyon Est, Université de Lyon, Lyon, France.
Centre de Référence des Maladies Rares du Calcium et du Phosphore, Unité d'Endocrinologie, Génétique et Pathologies Osseuses, Filières Santé Maladies Rares OSCAR et BOND, Hôpital des Enfants, Toulouse, France.
Arch Pediatr. 2022 May;29(4):312-325. doi: 10.1016/j.arcped.2022.02.008. Epub 2022 Mar 16.
Nutritional vitamin D supplements are often used in general pediatrics. Here, the aim is to address vitamin D supplementation and calcium nutritional intakes in newborns, infants, children, and adolescents to prevent vitamin D deficiency and rickets in general populations.
We formulated clinical questions relating to the following categories: the Patient (or Population) to whom the recommendation will apply; the Intervention being considered; the Comparison (which may be "no action," placebo, or an alternative intervention); and the Outcomes affected by the intervention (PICO). These PICO elements were arranged into the questions to be addressed in the literature searches. Each PICO question then formed the basis for a statement. The population covered consisted of children aged between 0 and 18 years and premature babies hospitalized in neonatology. Two groups were assembled: a core working group and a voting panel from different scientific pediatric committees from the French Society of Pediatrics and national scientific societies.
We present here 35 clinical practice points (CPPs) for the use of native vitamin D therapy (ergocalciferol, vitamin D and cholecalciferol, vitamin D) and calcium nutritional intakes in general pediatric populations.
This consensus document was developed to provide guidance to health care professionals on the use of nutritional vitamin D and dietary modalities to achieve the recommended calcium intakes in general pediatric populations. These CPPs will be revised periodically. Research recommendations to study key vitamin D outcome measures in children are also suggested.
营养性维生素 D 补充剂常用于儿科常规治疗。本研究旨在为新生儿、婴儿、儿童和青少年提供维生素 D 补充和钙营养摄入量的建议,以预防普通人群维生素 D 缺乏和佝偻病。
我们针对以下类别制定了临床问题:推荐将适用于的患者(或人群);正在考虑的干预措施;可能是“不采取行动”、安慰剂或替代干预措施的比较;以及干预措施影响的结果(PICO)。这些 PICO 元素被安排在文献检索中需要解决的问题中。每个 PICO 问题随后构成陈述的基础。所涵盖的人群包括 0 至 18 岁的儿童和在新生儿科住院的早产儿。我们组建了两个小组:一个核心工作组和一个来自法国儿科学会和国家科学学会不同儿科科学委员会的投票小组。
我们在此提出了 35 条临床实践要点(CPPs),用于一般儿科人群中使用天然维生素 D 治疗(麦角钙化醇、维生素 D 和胆钙化醇、维生素 D)和钙营养摄入量。
本共识文件旨在为医疗保健专业人员提供关于营养性维生素 D 和膳食方式的使用指南,以达到一般儿科人群推荐的钙摄入量。这些 CPP 将定期修订。还建议了研究关键维生素 D 儿童结局指标的研究建议。