利用计算机模拟方法估算不同物种牛奶中的生物活性肽含量。
Estimation of bioactive peptide content of milk from different species using an in silico method.
机构信息
Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Department of Community Nutrition, Faculty of Nutrition Science and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Amino Acids. 2023 Oct;55(10):1261-1278. doi: 10.1007/s00726-022-03152-6. Epub 2022 Mar 19.
This study assessed the bioactive peptides content of milk from different species, including humans, camel, bovine, buffalo, donkey, sheep, goat, and horse. The highest and lowest concentrations of total digestion-resistant peptides were estimated in sheep and human milk. Donkey milk casein contains a higher angiotensin-converting enzyme (ACE) inhibitory, dipeptidyl peptidase III (DPP-III) inhibitory, DPP-IV inhibitory, and antioxidant peptides. On the other hand, camel whey protein contains the highest ACE-inhibitory peptides. To discover BPs with immunomodulatory and cholesterol-lowering functions, goat milk casein and sheep milk whey protein can be considered, respectively.
本研究评估了来自不同物种（包括人类、骆驼、牛、水牛、驴、绵羊、山羊和马）的牛奶中的生物活性肽含量。在绵羊和人乳中，总消化抗性肽的最高和最低浓度被估计。驴乳酪蛋白含有更高的血管紧张素转换酶（ACE）抑制肽、二肽基肽酶 III（DPP-III）抑制肽、DPP-IV 抑制肽和抗氧化肽。另一方面，骆驼乳清蛋白含有最高的 ACE 抑制肽。为了发现具有免疫调节和降胆固醇功能的 BP，可以分别考虑山羊奶酪蛋白和绵羊乳清蛋白。
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