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实施药剂师主导的过渡性药物治疗计划:通过社区和医院药剂师之间的合作减少住院人数的药物行动(MARCH)的过程评估。

Implementation of a pharmacist-led transitional pharmaceutical care programme: Process evaluation of Medication Actions to Reduce hospital admissions through a collaboration between Community and Hospital pharmacists (MARCH).

机构信息

Department of Clinical Pharmacology and Pharmacy, Amsterdam UMC, Amsterdam, The Netherlands.

Department of Clinical Pharmacy, OLVG, Amsterdam, The Netherlands.

出版信息

J Clin Pharm Ther. 2022 Jul;47(7):1049-1069. doi: 10.1111/jcpt.13645. Epub 2022 Mar 20.

Abstract

WHAT IS KNOWN AND OBJECTIVE

The recently conducted Medication Actions to Reduce hospital admissions through a collaboration between Community and Hospital pharmacists (MARCH) transitional care programme, which aimed to test the effectiveness of a transitional care programme on the occurrence of ADEs post-discharge, did not show a significant effect. To clarify whether this non-significant effect was due to poor implementation or due to ineffectiveness of the intervention as such, a process evaluation was conducted. The aim of the study was to gain more insight into the implementation fidelity of MARCH.

METHODS

A mixed methods design and the modified Conceptual Framework for Implementation Fidelity was used. For evaluation, the implementation fidelity and moderating factors of four key MARCH intervention components (teach-back, the pharmaceutical discharge letter, the post-discharge home-visit and the transitional medication review) were assessed. Quantitative data were collected during and after the intervention. Qualitative data were collected using semi-structured interviews with MARCH healthcare professionals (community pharmacists, clinical pharmacists, pharmacy assistants and pharmaceutical consultants) and analysed using thematic analysis.

RESULTS AND DISCUSSION

Not all key intervention components were implemented as intended. Teach-back was not always performed. Moreover, 63% of the pharmaceutical discharge letters, 35% of the post-discharge home-visits and 44% of the transitional medication reviews were not conducted within their planned time frames. Training sessions, structured manuals and protocols with detailed descriptions facilitated implementation. Intervention complexity, time constraints and the multidisciplinary coordination were identified as barriers for the implementation.

WHAT IS NEW AND CONCLUSION

Overall, the implementation fidelity was considered to be moderate. Not all key intervention components were carried out as planned. Therefore, the non-significant results of the MARCH programme on ADEs may at least partly be explained by poor implementation of the programme. To successfully implement transitional care programmes, healthcare professionals require full integration of these programmes in the standard work-flow including IT improvements as well as compensation for the time investment.

摘要

已知和目的

最近开展的 Medication Actions to Reduce hospital admissions through a collaboration between Community and Hospital pharmacists (MARCH) 过渡护理计划旨在测试过渡护理计划对出院后 ADE 发生的效果,并没有显示出显著的效果。为了明确这种非显著效果是由于实施不力还是干预本身无效,进行了过程评估。该研究的目的是更深入地了解 MARCH 的实施保真度。

方法

采用混合方法设计和修改后的实施保真度概念框架。为了评估,评估了 MARCH 四个关键干预组件(回授、药品出院信、出院后家访和过渡药物审查)的实施保真度和调节因素。定量数据在干预期间和之后收集。定性数据通过对 MARCH 医疗保健专业人员(社区药剂师、临床药剂师、药剂助理和药剂顾问)的半结构化访谈收集,并使用主题分析进行分析。

结果与讨论

并非所有关键干预组件都按计划实施。回授并不总是执行。此外,63%的药品出院信、35%的出院后家访和 44%的过渡药物审查未在计划的时间框架内进行。培训课程、带有详细说明的结构化手册和协议促进了实施。干预复杂性、时间限制和多学科协调被确定为实施的障碍。

新内容和结论

总体而言,实施保真度被认为是中等的。并非所有关键干预组件都按计划进行。因此,MARCH 计划在 ADE 方面的非显著结果至少部分可以解释为计划实施不力。要成功实施过渡护理计划,医疗保健专业人员需要将这些计划完全整合到标准工作流程中,包括 IT 改进以及对时间投入的补偿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b320/9544789/7a69a1b49cbc/JCPT-47-1049-g001.jpg

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