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从. 中分离得到三个新的色烯和一个新的黄酮苷。

Three new chromanes and one new flavone -glycoside from .

机构信息

Graduate University of Science and Technology, Vietnam Academy of Science and Technology (VAST), Hanoi 10072, Vietnam.

Faculty of Chemistry, Thai Nguyen University of Sciences, Thai Nguyen 24118, Vietnam.

出版信息

J Asian Nat Prod Res. 2023 Jan;25(1):18-26. doi: 10.1080/10286020.2022.2051494. Epub 2022 Mar 20.

Abstract

Three new chromanes, malloapeltas J-L (-), and one new flavone -glycoside, malloflavoside (), together with four known compounds, apigenin 6---D-xylopyranosyl-8---L-arabinopyranoside (), apigenin 6---D-glucopyranosyl-8---L-arabinopyranoside (), apigenin 7---D-apiofuranosyl-(1→2)--D-glucopyranoside (), and acantrifoside E () were isolated from the methanol extract of the leaves of . Their chemical structures were determined using spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS methods. All the isolated compounds were evaluated their cytotoxic activity against human prostate cancer (PC-3) and human breast cancer (MCF-7) cells, but none of them showed cytotoxicities on both human cancer cell lines.

摘要

从的甲醇提取物中分离得到三个新的 chromanes,malloapeltas J-L (-),和一个新的黄酮苷,mallooflavoside (),以及四个已知化合物,芹菜素 6---D-木吡喃糖基-8---L-阿拉伯吡喃糖苷 (),芹菜素 6---D-吡喃葡萄糖基-8---L-阿拉伯吡喃糖苷 (),芹菜素 7---D-阿戊呋喃糖基-(1→2)--D-吡喃葡萄糖苷 ()和 acantrifoside E ()。采用 1D、2D NMR 和 HR-ESI-MS 等光谱方法确定了它们的化学结构。所有分离得到的化合物均对人前列腺癌细胞 (PC-3) 和人乳腺癌细胞 (MCF-7) 进行了细胞毒性活性评价,但对这两种人癌细胞系均无细胞毒性。

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