Department of Pharmaceutical Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University (PNU), Riyadh, Saudi Arabia.
Pediatr Endocrinol Diabetes Metab. 2022;28(1):54-63. doi: 10.5114/pedm.2022.113988.
Quality of life (QoL) in adolescent patients suffering from type 2 diabetes mellitus (T2DM) has not been thoroughly explored in Saudi Arabia. Herein, we aimed to measure the health-related quality of life (HRQoL) in adolescent patients suffering from T2DM and explore the correlation between adolescents' self- and parent-reporting of QoL scores, and glycaemic control (HbA1c).
A retrospective multi-centre cohort study was conducted at 4 hospitals in Riyadh, Saudi Arabia. The Paediatric Quality of Life Inventory (PedsQLTM) Diabetes Module 3.0 was completed by children and their parents in a confidential and anonyms manner through a phone interview.
We recruited 49 paediatric patients for this study (mean age: 18.45 years; male: 55%). Both children and parents reported low cumulative mean scores for PedsQL™ (58.65 and 57.38, respectively) as compared to previous international studies. The lowest obtained score was noted for the diabetes symptoms domain (53.4). Comparing the magnitude of discrepancy between the adolescents' and parents' subscale scores revealed a non-significant difference, except for the 'worry' subscale, in which parents reported significantly higher mean scores (76.73 vs. 60.54, p = 0.02). Comparison of mean scores reported by adolescents who met the target HbA1c goal (<7%) and their counterparts revealed a non-significant difference, suggesting an irrelevant impact of this parameter on their perspectives or experiences.
The study findings emphasized the need to initiate further intensive awareness programs concerning this disease and its clinical implications in T2DM children to improve treatment adherence and symptoms, and consequently improve the perception of the patient and the family for HRQoL.
在沙特阿拉伯，尚未深入探讨 2 型糖尿病（T2DM）青少年患者的生活质量（QoL）。在此，我们旨在测量患有 T2DM 的青少年患者的健康相关生活质量（HRQoL），并探讨青少年自我报告和父母报告的 QoL 评分与血糖控制（HbA1c）之间的相关性。
这是一项在沙特阿拉伯利雅得的 4 家医院进行的回顾性多中心队列研究。通过电话访谈以保密和匿名的方式，由儿童及其父母完成儿童生活质量问卷（PedsQLTM）糖尿病模块 3.0。
本研究共招募了 49 名儿科患者（平均年龄：18.45 岁；男性：55%）。与以前的国际研究相比，儿童和父母报告的 PedsQL™累积平均得分均较低（分别为 58.65 和 57.38）。获得的最低分数是糖尿病症状领域（53.4）。比较青少年和父母亚量表得分之间差异的幅度，除了“担忧”亚量表外，差异无统计学意义，父母报告的平均得分显著更高（76.73 与 60.54，p = 0.02）。将达到 HbA1c 目标（<7%）的青少年与未达到该目标的青少年的平均得分进行比较，结果显示差异无统计学意义，表明该参数对他们的观点或体验无明显影响。
研究结果强调需要启动进一步的强化意识计划，以提高治疗依从性和改善症状，从而改善 T2DM 儿童对疾病及其临床意义的认识，提高患者和家庭对 HRQoL 的感知。
