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病例报告：从巴西中西部一名流产患者的胎盘中分离出新型冠状病毒伽马变异株。

Case Report: SARS-CoV-2 Gamma Isolation From Placenta of a Miscarriage in Midwest, Brazil.

作者信息

Fernandez Zoraida, Lichs Gislene G C, Zubieta Claudia S, Machado Ana B, Ferreira Mia A, Valente Natalia, Keren Thayssa, Arantes Ighor, Nacife Valeria, Pereira Elisa Cavalcante, Appolinario Luciana, Lacerda Thays E J, Siqueira Marilda M, Esposito Ana O P, Demarchi Luiz H F, Zardin Marina C S U, Goncalves Crhistinne C M, Maziero Livia M A, Miziara Luciana A F, Naveca Felipe G, Pauvolid-Corrêa Alex, Resende Paola C, Favacho Alexsandra R M

机构信息

Fundação Oswaldo Cruz (Fiocruz), Campo Grande , Brazil.

Laboratório Central de Saúde Pública, Campo Grande , Brazil.

出版信息

Front Med (Lausanne). 2022 Mar 4;9:839389. doi: 10.3389/fmed.2022.839389. eCollection 2022.

DOI:10.3389/fmed.2022.839389
PMID:35308526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8931541/
Abstract

The present study investigated a SARS-CoV-2 infection in placenta and fetal samples from an early pregnancy miscarriage in Midwest Brazil. The Gamma variant was isolated and fully sequenced from the placenta sample, but not from fetal samples. Our findings highlight potential adverse perinatal outcomes caused by SARS-CoV-2 Gamma infection during pregnancy.

摘要

本研究调查了巴西中西部地区一例早孕流产的胎盘和胎儿样本中的新冠病毒感染情况。从胎盘样本中分离出了伽马变异株并进行了全基因组测序，但胎儿样本中未分离出。我们的研究结果突出了孕期感染新冠病毒伽马变异株可能导致的不良围产期结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd8f/8931541/069c02544036/fmed-09-839389-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd8f/8931541/574aea50725d/fmed-09-839389-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd8f/8931541/069c02544036/fmed-09-839389-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd8f/8931541/574aea50725d/fmed-09-839389-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd8f/8931541/069c02544036/fmed-09-839389-g0002.jpg

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Biochim Biophys Acta Mol Basis Dis. 2021 Dec 1;1867(12):166248. doi: 10.1016/j.bbadis.2021.166248. Epub 2021 Aug 28.
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Editorial: Maternal SARS-CoV-2 Infection and Pregnancy Outcomes from Current Global Study Data.社论：当前全球研究数据显示，产妇感染 SARS-CoV-2 与妊娠结局。
Med Sci Monit. 2021 Jul 5;27:e933831. doi: 10.12659/MSM.933831.
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COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P.1 emergence.
巴西亚马逊地区的 COVID-19 是由地方性谱系的持续存在和 P.1 出现驱动的。
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Maternal Coronavirus Infections and Neonates Born to Mothers with SARS-CoV-2: A Systematic Review.母亲感染冠状病毒及感染新冠病毒的母亲所生新生儿：一项系统评价
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Maternal and perinatal outcomes in pregnant women infected by SARS-CoV-2: A meta-analysis.孕妇感染 SARS-CoV-2 的母婴围生结局：一项荟萃分析。
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