Grupo de Pesquisa em Bioestatística e Epidemiologia Molecular, Laboratório de Biologia Integrativa, Programa de Pós-Graduação em Genética, Departamento de Genética, Ecologia e Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Viruses. 2022 Dec 5;14(12):2715. doi: 10.3390/v14122715.
Several studies have monitored the SARS-CoV-2 variants in Brazil throughout the pandemic. Here, we systematically reviewed and conducted a scientometric analysis of the SARS-CoV-2 genomic surveillance studies using Brazilian samples. A Pubmed database search on October 2022 returned 492 articles, of which 106 were included. Ninety-six different strains were reported, with variant of concern (VOC) gamma ( = 35,398), VOC delta ( = 15,780), and the variant of interest zeta ( = 1983) being the most common. The top three states with the most samples in the published articles were São Paulo, Rio de Janeiro, and Minas Gerais. Whereas the first year of the pandemic presented primary circulation of B.1.1.28 and B.1.1.33 variants, consecutive replacements were observed between them and VOI zeta, VOC gamma, VOC delta, and VOC omicron. VOI mu, VOI lambda, VOC alpha, and VOC beta were also detected but failed to reach significant circulation. Co-infection, re-infection, and vaccine breakthrough reports were found. Article co-citation differed from the co-authorship structure. Despite the limitations, we expect to give an overview of Brazil's genomic surveillance studies and contribute to future research execution.
已有多项研究在疫情期间对巴西的 SARS-CoV-2 变体进行了监测。在这里，我们系统性地回顾和进行了一项关于使用巴西样本的 SARS-CoV-2 基因组监测研究的科学计量分析。2022 年 10 月在 Pubmed 数据库中的搜索返回了 492 篇文章，其中 106 篇被纳入。报告了 96 种不同的菌株，其中关切变体 (VOC) 伽马（=35398）、VOC 德尔塔（=15780）和关注变体 zeta（=1983）最为常见。发表文章中样本数量最多的三个州是圣保罗、里约热内卢和米纳斯吉拉斯。虽然大流行的第一年主要循环的是 B.1.1.28 和 B.1.1.33 变体，但随后在它们与 VOI zeta、VOC 伽马、VOC 德尔塔和 VOC 奥密克戎之间出现了连续的更替。也检测到了 VOI mu、VOI lambda、VOC alpha 和 VOC beta，但未能达到显著的循环水平。还发现了合并感染、再感染和疫苗突破的报告。文章共被引与合著结构不同。尽管存在局限性，但我们希望对巴西的基因组监测研究进行概述，并为未来的研究执行做出贡献。
