Ward M, Halliday C, Cowen A E
Digestion. 1986;34(3):173-7. doi: 10.1159/000199326.
In a randomized, endoscopically controlled trial, the effects of colloidal bismuth subcitrate (CBS) tablets on the healing of chronic duodenal ulcers were compared with those of ranitidine (R). 38 patients were originally allocated to the CBS group and 37 to ranitidine. There were 5 dropouts in each group. Of 33 patients given CBS, 25 (75%) showed complete ulcer healing by 4 weeks and 30 (91%) by 8 weeks. Of the 32 patients given ranitidine, 28 (87%) showed complete ulcer healing by 4 weeks and 30 (94%) by 8 weeks. There was no significant difference between these results. Symptom resolution was similar in both groups and no significant adverse effects were noted.
在一项随机、内镜对照试验中，比较了枸橼酸铋钾（CBS）片与雷尼替丁（R）对慢性十二指肠溃疡愈合的影响。最初38例患者被分配至CBS组，37例患者被分配至雷尼替丁组。每组各有5例退出。给予CBS的33例患者中，25例（75%）在4周时溃疡完全愈合，30例（91%）在8周时溃疡完全愈合。给予雷尼替丁的32例患者中，28例（87%）在4周时溃疡完全愈合，30例（94%）在8周时溃疡完全愈合。这些结果之间无显著差异。两组症状缓解情况相似，未观察到显著不良反应。
