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COVID-19感染后肝硬化迅速转变为肝性脑病:一则警示故事

Rapid Turn From Cirrhosis to Encephalopathy Following COVID-19 Infection: A Cautionary Tale.

作者信息

Chowdhury Tutul, Sultana Jakia, Dutta Jui, Gousy Nicole, Hassan Khondokar N

机构信息

Internal Medicine, One Brooklyn Health System, New York, USA.

Medicine, Comilla Medical College, Cumilla, BGD.

出版信息

Cureus. 2022 Feb 10;14(2):e22089. doi: 10.7759/cureus.22089. eCollection 2022 Feb.

Abstract

The coronavirus disease 2019 (COVID-19) infection has most commonly led to patients presenting with pulmonary disease, including severe acute respiratory syndrome. However, in about 14-53% of patients with a newly diagnosed COVID-19 infection, the liver is the organ most drastically affected, as opposed to the lungs. In patients with preexisting liver damage, the first symptom of a COVID-19 infection may come from worsening liver failure such as hepatic encephalopathy or worsening ascites. This case report highlights this unusual presentation of a COVID-19 infection in a patient with preexisting alcoholic liver cirrhosis. We report this case to heed warning that acutely worsening liver failure may be the first presenting symptom of a superimposed COVID-19 infection on preexisting liver disease.

摘要

2019冠状病毒病(COVID-19)感染最常导致患者出现肺部疾病,包括严重急性呼吸综合征。然而,在新诊断的COVID-19感染患者中,约14%至53%的患者肝脏是受影响最严重的器官,而非肺部。在已有肝损伤的患者中,COVID-19感染的首发症状可能来自肝功能衰竭恶化,如肝性脑病或腹水加重。本病例报告突出了一名已有酒精性肝硬化患者COVID-19感染的这种不寻常表现。我们报告此病例以提醒注意,急性肝功能衰竭恶化可能是COVID-19感染叠加于已有肝病时的首发症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51fe/8920829/bf1c373902bc/cureus-0014-00000022089-i01.jpg

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