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NGS in CML - New standard diagnostic procedure?

作者信息

Branford Susan, Shanmuganathan Naranie

机构信息

Department of Genetics and Molecular Pathology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.

School of Pharmacy and Medical Science, University of South Australia, Adelaide, Australia.

出版信息

Hemasphere. 2019 Jun 30;3(Suppl). doi: 10.1097/HS9.0000000000000199. eCollection 2019 Jun.

DOI:10.1097/HS9.0000000000000199
PMID:35309784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8925682/
Abstract
摘要

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The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers.COSMIC 癌症基因目录：描述所有人类癌症中的遗传功能障碍。
Nat Rev Cancer. 2018 Nov;18(11):696-705. doi: 10.1038/s41568-018-0060-1.
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Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high-risk disease.综合基因组分析揭示了高危疾病患者 CML 诊断时与癌症相关的突变。
分子亚型可预测治疗反应，并基于机器学习在慢性髓性白血病中识别和验证诊断特征。
Cancer Cell Int. 2023 Apr 6;23(1):61. doi: 10.1186/s12935-023-02905-x.
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An interesting case of chronic myeloid leukemia with twists and turns.一例曲折多变的慢性髓系白血病有趣病例。
Hematol Transfus Cell Ther. 2024 Dec;46 Suppl 6(Suppl 6):S385-S388. doi: 10.1016/j.htct.2023.02.001. Epub 2023 Mar 7.
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Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs: A literature review.慢性髓性白血病——从费城染色体到特异性靶向药物：文献综述
World J Clin Oncol. 2021 Feb 24;12(2):69-94. doi: 10.5306/wjco.v12.i2.69.
Blood. 2018 Aug 30;132(9):948-961. doi: 10.1182/blood-2018-02-832253. Epub 2018 Jul 2.
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Frequent ASXL1 mutations in children and young adults with chronic myeloid leukemia.慢性髓性白血病儿童和青年中ASXL1突变频繁。
Leukemia. 2018 Sep;32(9):2046-2049. doi: 10.1038/s41375-018-0157-2. Epub 2018 Jun 13.
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Somatic mutations identified at diagnosis by exome sequencing can predict response to imatinib in chronic phase chronic myeloid leukemia (CML) patients.通过外显子组测序在诊断时鉴定出的体细胞突变可预测慢性期慢性髓性白血病（CML）患者对伊马替尼的反应。
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