Hubei Provincial Hospital of Traditional Chinese Medicine, Dermatological Department, Attending Psychiatrist, 430061, China.
Hubei Provincial Hospital of Traditional Chinese Medicine, Dermatological Department, Supervising Technician, 430061, China.
Comput Math Methods Med. 2022 Mar 11;2022:1636839. doi: 10.1155/2022/1636839. eCollection 2022.
Rose acne is a chronic inflammatory skin disease that can cause paroxysmal flushing, persistent erythema, papules or papules on the face, and pustules, and it has a greater impact on the life of patients, so it is important to treat it.
To investigate the effect of Danzhi Xiaoyao Powder combined with photodynamic therapy (PDT) on the curative effect evaluation and prognosis of patients with rose acne. . The clinical data of 110 rose acne patients who were treated in our hospital from January 2019 to January 2021 were selected as the subject of this retrospective study. They were divided into a control group and a treatment group according to the random residue grouping method. The new crown epidemic, loss to follow-up, etc. fell out of 5 cases in each group, and finally, 50 cases in each group were left. Among them, the control group was treated with PDT, and the treatment group was combined with Danzhi Xiaoyao Powder on the basis of the control group. Then we observe and compare the effects of skin lesion scores and clinical symptom scores and differences in clinical efficacy between the two groups.
The comparison of the clinical symptom scores of the two groups of patients before treatment was not statistically significant ( > 0.05), while the burning score, tingling score, dryness score, and pruritus score of the treatment group after treatment were significantly different. The internal comparison after treatment was lower than before treatment, and the comparison between the treatment groups was significantly higher than the control group, which was statistically significant ( < 0.05). There was no statistically significant difference in the skin lesion scores of the two groups before treatment ( > 0.05), while the papules score, pustule score, erythema score, and telangiectasia score of the treatment group after treatment were significantly different and compared within the group. After treatment, the treatment group was significantly higher than the control group, and the comparison was statistically significant ( < 0.05). The effective rate of 98.00% in the treatment group was significantly higher than the 76.00% in the control group, and the difference was statistically significant ( < 0.05). The clinical efficacy of the two groups of patients showed that the rash, chest tightness, nausea, and diarrhea of the treatment group were significantly lower than those of the control group, and the difference was statistically significant ( < 0.05).
Danzhi Xiaoyao Powder combined with PDT to treat rose acne is effective, can quickly control inflammatory papules and inflammatory erythema, effectively improve the clinical symptoms of patients, and reduce adverse reactions.
玫瑰痤疮是一种慢性炎症性皮肤病，可引起阵发性潮红、持续性红斑、丘疹或脓疱，对患者的生活影响较大，因此治疗非常重要。
探讨丹栀逍遥散联合光动力疗法（PDT）对玫瑰痤疮患者疗效评价及预后的影响。
回顾性分析 2019 年 1 月至 2021 年 1 月在我院治疗的 110 例玫瑰痤疮患者的临床资料，按照随机余数分组法将其分为对照组和治疗组，每组各 50 例。其中，对照组采用 PDT 治疗，治疗组在对照组的基础上联合丹栀逍遥散治疗。观察比较两组患者皮损评分、临床症状评分及临床疗效的差异。
两组患者治疗前临床症状评分比较差异无统计学意义（>0.05），治疗后治疗组烧灼感评分、刺痛感评分、干燥感评分、瘙痒感评分均较治疗前明显降低，组内比较差异均有统计学意义（<0.05），且与对照组比较差异均有统计学意义（<0.05）。两组患者治疗前皮损评分比较差异无统计学意义（>0.05），治疗后治疗组丘疹评分、脓疱评分、红斑评分、毛细血管扩张评分均较治疗前明显升高，组内比较差异均有统计学意义（<0.05），且与对照组比较差异均有统计学意义（<0.05）。治疗组总有效率为 98.00%，明显高于对照组的 76.00%，差异有统计学意义（<0.05）。两组患者治疗后不良反应发生率比较差异有统计学意义（<0.05），治疗组皮疹、胸闷、恶心、腹泻发生率均明显低于对照组。
丹栀逍遥散联合 PDT 治疗玫瑰痤疮疗效确切，能快速控制炎症性丘疹和炎症性红斑，有效改善患者的临床症状，降低不良反应发生率。
