Alrusayyis Danah, Aljubran Hussain, Alshaibani Askar, Alsharhan Salma, AlSaied Abdulmalik, ALEnazi Abdulaziz, Alghamdi Amal, Alshahrani Saad, Salam Abdul, Al Bar Mohammed
Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
King Fahad Specialist Hospital, Dammam, Saudi Arabia.
J Prim Care Community Health. 2022 Jan-Dec;13:21501319221084158. doi: 10.1177/21501319221084158.
Many studied investigated the manifestations of COVID-19, yet few described the pattern and severity of otolaryngological symptoms. We aim to describe the picture of COVID-19-associated otorhinolaryngological manifestations and recovery to explore individualized treatment, onward referral, and complications prevention.
Prospective longitudinal questionnaire-based study.
The online questionnaire was filled 3 times through a remote interview over a period of 1 month from June 2020 to July 2020.
Patients with confirmed COVID-19 by RT-PCR who were clinically stable.
Date of diagnosis, sociodemographic data, and the presence of predictive factors, such as nasal and paranasal disease, anosmia and dysgeusia. Validated tools were used, such as Sino-nasal Outcome Test (SNOT-22), smell test (medical academy screening tool), Voice Handicap Index (VHI), and Reflux Symptoms Index (RSI).
The questionnaire was sent to 363 patients and the response rate was 70.80% (n = 257). The mean age was 34.58 years (SD = 11.22) and the rate of male participants was 60.7%. The most common otorhinolaryngological symptoms at the time of enrollment was fever (48.6%), whilst the commonest severe symptom was cough (57%). After 1 month, only 11 participants had persistent severe symptoms, especially sleep and psychological symptoms (73%), and the majority were female (63.6%). All of them had at least 1 comorbidity. There was a significant difference between the mean age of participants with severe symptoms (mean = 27.45, SD = 8.39) and without severe symptoms (mean = 34.90, SD = 2.53, (255) = 2.17, = .031).
COVID-19 has a wide-ranged spectrum of presentations, with otorhinolaryngological symptoms being the commonest and most serious. Studying these symptoms is vital to advance management options.
许多研究调查了新型冠状病毒肺炎（COVID-19）的表现，但很少有人描述耳鼻喉科症状的模式和严重程度。我们旨在描述与COVID-19相关的耳鼻喉科表现及恢复情况，以探索个体化治疗、进一步转诊和预防并发症。
基于问卷的前瞻性纵向研究。
2020年6月至2020年7月期间，通过远程访谈分3次填写在线问卷。
经逆转录聚合酶链反应（RT-PCR）确诊为COVID-19且临床稳定的患者。
诊断日期、社会人口统计学数据以及预测因素的存在情况，如鼻和鼻窦疾病、嗅觉丧失和味觉障碍。使用了经过验证的工具，如鼻-鼻窦结局测试（SNOT-22）、嗅觉测试（医学院筛查工具）、嗓音障碍指数（VHI）和反流症状指数（RSI）。
向363名患者发送了问卷，回复率为70.80%（n = 257）。平均年龄为34.58岁（标准差=11.22），男性参与者比例为60.7%。入组时最常见的耳鼻喉科症状是发热（48.6%），而最常见的严重症状是咳嗽（57%）。1个月后，只有11名参与者有持续的严重症状，尤其是睡眠和心理症状（73%），且大多数为女性（63.6%）。他们都至少有一种合并症。有严重症状的参与者（平均年龄=27.45，标准差=8.39）与无严重症状的参与者（平均年龄=34.90，标准差=2.53，t(255)=2.17，P = 0.031）的平均年龄存在显著差异。
COVID-19有广泛的表现谱，耳鼻喉科症状是最常见和最严重的。研究这些症状对于推进管理方案至关重要。
