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加利福尼亚州欧隆尼原住民的古今基因组学研究。

Ancient and modern genomics of the Ohlone Indigenous population of California.

机构信息

Department of Genetics, Stanford University, Stanford, CA 94305.

Far Western Anthropological Research Group, Davis, CA 95618.

出版信息

Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2111533119. doi: 10.1073/pnas.2111533119. Epub 2022 Mar 21.

DOI:10.1073/pnas.2111533119
PMID:35312358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9060455/
Abstract

SignificanceCalifornia supports a high cultural and linguistic diversity of Indigenous peoples. In a partnership of researchers with the Muwekma Ohlone tribe, we studied genomes of eight present-day tribal members and 12 ancient individuals from two archaeological sites in the San Francisco Bay Area, spanning ∼2,000 y. We find that compared to genomes of Indigenous individuals from throughout the Americas, the 12 ancient individuals are most genetically similar to ancient individuals from Southern California, and that despite spanning a large time period, they share distinctive ancestry. This ancestry is also shared with present-day tribal members, providing evidence of genetic continuity between past and present Indigenous individuals in the region, in contrast to some popular reconstructions based on archaeological and linguistic information.

摘要

意义加利福尼亚州支持原住民拥有高度的文化和语言多样性。在与 Muwekma Ohlone 部落的研究人员合作中,我们研究了来自旧金山湾区两个考古地点的 8 名当代部落成员和 12 名古代个体的基因组,跨度约 2000 年。我们发现,与来自整个美洲的原住民个体的基因组相比,这 12 名古代个体与来自南加州的古代个体在基因上最为相似,而且尽管时间跨度很大,但他们具有独特的祖先。这种祖先也与当代部落成员共享,为该地区过去和现在的原住民个体之间存在遗传连续性提供了证据,这与基于考古学和语言学信息的一些流行重建形成了对比。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/224306c6deef/pnas.2111533119fig07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/96b00c4d9c13/pnas.2111533119fig01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/f46cf31257f4/pnas.2111533119fig02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/4ac8ff4e13f3/pnas.2111533119fig03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/d1708f3abe68/pnas.2111533119fig04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/e95daebec460/pnas.2111533119fig05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/b3a5919eb376/pnas.2111533119fig06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/224306c6deef/pnas.2111533119fig07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/96b00c4d9c13/pnas.2111533119fig01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/f46cf31257f4/pnas.2111533119fig02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/4ac8ff4e13f3/pnas.2111533119fig03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/d1708f3abe68/pnas.2111533119fig04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/e95daebec460/pnas.2111533119fig05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/b3a5919eb376/pnas.2111533119fig06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143f/9060455/224306c6deef/pnas.2111533119fig07.jpg

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