严重急性呼吸综合征冠状病毒 2 型间质性肺炎后出现的平卧位呼吸困难-直立性低氧血症综合征：病例概述及患者最新情况。

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Acta Biomed. 2022 Mar 14;93(1):e2022015. doi: 10.23750/abm.v93i1.11814.

Platypnea-Orthodeoxia Syndrome (POS) is a clinical entity defined as positional dyspnoea (platypnea) and arterial desaturation (orthodeoxia) that occurs when sitting or standing up and usually resolves by lying down. Up to April 25th 2021, eleven cases of POS after SARS-CoV-2 pneumonia have been reported on Pubmed. Accordingly, SARS-CoV-2 infection may be considered as an emergent cause of POS due to an increase in ventilation/perfusion (V/Q) mismatch. In this article we provide an update on the patient with POS after fibrotic evolution of SARS-CoV-2 interstitial pneumonia, which we previously reported and we discuss the case reports of POS due to SARS-CoV-2 infection.

体位性呼吸困难-低氧血症综合征（POS）是一种临床病症，定义为当坐立或站立时出现呼吸困难（体位性呼吸困难）和动脉血氧饱和度降低（低氧血症），而当躺下时通常会缓解。截至 2021 年 4 月 25 日，在 Pubmed 上已报告了 11 例 SARS-CoV-2 肺炎后 POS 病例。因此，由于通气/血流（V/Q）不匹配增加，SARS-CoV-2 感染可被视为 POS 的一个新出现病因。在本文中，我们对先前报道的纤维化演变后的 SARS-CoV-2 间质性肺炎后出现 POS 的患者进行了更新，并讨论了因 SARS-CoV-2 感染而出现 POS 的病例报告。