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COVID-19 相关肝损伤:病理发现。

Liver injury in COVID-19: pathological findings.

机构信息

Department of Pathology, Habib Bourguiba University Hospital, El Ain, Sfax, Tunisia.

出版信息

Pan Afr Med J. 2022 Jan 20;41:56. doi: 10.11604/pamj.2022.41.56.31114. eCollection 2022.

Abstract

Hepatic injuries have been reported in patients with Coronavirus disease 2019 infection, particularly in those with moderate to severe illness. To date, pathological changes caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in liver tissue are unclear. Moreover, the mechanisms involved in liver injury in Coronavirus disease 2019 infection are not yet established. In this paper, we summarize the spectrum of pathologic findings of liver injury in patients infected by SARS-CoV-2 and we discuss the clinicopathological correlation and the mechanisms of liver damage in Coronavirus disease 2019 infection.

摘要

据报道,2019 年冠状病毒病(COVID-19)感染患者存在肝损伤,特别是在中度至重度疾病患者中。迄今为止,严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)引起的肝组织病理变化尚不清楚。此外,COVID-19 感染导致肝损伤的机制尚不清楚。在本文中,我们总结了感染 SARS-CoV-2 的患者的肝损伤病理发现谱,并讨论了 COVID-19 感染中肝损伤的临床病理相关性和机制。

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