Department of Stomatology, Faculty of Dentistry, University of Seville, Seville 41009, Spain.
Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, Madrid 28040, Spain.
J Stomatol Oral Maxillofac Surg. 2022 Oct;123(5):e367-e375. doi: 10.1016/j.jormas.2022.03.014. Epub 2022 Mar 19.
Oroantral communication (OAC) is the opening between the maxillary sinus and the oral cavity, which constitutes a gate for the mucosal infection in the maxillary sinus. On the other hand, an OAF develops when the OAC does not close spontaneously, remains manifest and is epithelialized. Several methods have been proposed to solve these situations, however, they are associated with increased postoperative morbidity and/or higher associated costs and require some experience of the surgeon to perform them. To overcome these disadvantages, the use of Platelet-Rich Fibrin (PRF) is proposed. The present study aims to perform a systematic review of the literature, collecting cases in which PRF was used in the treatment of OACs/OAFs.
An electronic search of the MEDLINE database (via PubMed) and Web of Science was performed using the following MeSH terms (Medical Subjects Headings): (oroantral communication OR oroantral fistula OR buccosinusal communication) AND (platelet-rich fibrin OR prf OR fibrin mesh). The criteria used were those described by the PRISMA® Statement. The search was not time-restricted and was updated to April 2021.
After searching, 11 articles were included that met the established criteria. In these, PRF was used alone or in combination with bi- or trilaminar techniques achieving complete resolution in 100% of cases (n = 116).
With the limitations of this study, it can be established that PRF can be used alone for the treatment of OACs/OAFs up to 5 mm and, in larger defects, it is advisable to combine it with bi- or trilaminar techniques. PRF is an effective therapeutic option, with minimal associated postoperative morbidity compared to other techniques and allows the position of the mucogingival junction to be preserved. Its combination with bone grafting improves the starting point before the replacement of the missing tooth with a dental implant.
上颌窦与口腔之间的开口称为窦口,窦口是上颌窦黏膜感染的门户。另一方面,如果窦口不能自发关闭,仍然存在并被上皮化,则会形成上颌窦口腔瘘。已经提出了几种方法来解决这些情况,但这些方法与术后发病率增加和/或更高的相关成本相关,并且需要外科医生具有一定的经验才能实施。为了克服这些缺点,提出使用富含血小板的纤维蛋白(PRF)。本研究旨在对文献进行系统评价,收集使用 PRF 治疗窦口/瘘的病例。
通过 PubMed 对 MEDLINE 数据库进行电子检索,并使用以下 MeSH 术语(医学主题词)对 Web of Science 进行检索:(窦口沟通或窦口瘘或颊窦沟通)和(富含血小板的纤维蛋白或 PRF 或纤维蛋白网)。使用的标准是 PRISMA®声明中描述的标准。搜索无时间限制,并更新至 2021 年 4 月。
搜索后,符合既定标准的 11 篇文章被纳入。在这些文章中,PRF 单独使用或与双或三层技术联合使用,在 100%的病例(n=116)中实现了完全愈合。
受本研究的限制,可以确定 PRF 可单独用于治疗 5mm 以下的窦口/瘘,在较大的缺损中,建议将其与双或三层技术联合使用。PRF 是一种有效的治疗选择,与其他技术相比,术后发病率较低,并且允许保留黏牙龈交界处的位置。与骨移植结合使用可改善在缺失牙用种植牙替代之前的起始点。