Second Clinical Division, School and Hospital of Stomatology, Peking University, Beijing, 100101, China.
Department of Stomatological Technology, School of Stomatology, Shandong First Medical University, Jinan, 250117, Shandong, China.
Tissue Eng Regen Med. 2024 Aug;21(6):959-967. doi: 10.1007/s13770-024-00654-0. Epub 2024 Jun 28.
Classical guided bone regeneration (GBR) treatments can achieve favorable clinical results for ridge defects. However, extensive bone augmentation in the non-esthetic area in the posterior region for minor ridge defects is unnecessary. Therefore, this study used a collagen and Platelet-rich fibrin (PRF) mixture for bone augmentation on minor posterior ridge defects and evaluated the effects.
22 Seibert Class I ridge defects were treated with BC and covered with a PRF membrane (simplified guided bone regeneration, simplified GBR) and other 22 were treated with Bio-Oss and covered with Bio-Gide (classical GBR). Cone-beam computed tomography imaging was conducted 6 months post-surgery to compare the ridge's horizontal width (HW) and buccal ridge's horizontal width to assess the osteogenic effect. In addition, the buccal ridge contour morphology was studied and classified.
The buccal ridge contour of simplified GBR was Type A in 14 cases, Type B in 7 cases, and Type C in 1 case and it of classical GBR was Type A in 11 cases, Type B in 8 cases, and Type C in 3 cases. The mean HW significantly increased by 1.50 mm of simplified GBR treatment, while it increased by 1.83 mm in classical GBR treatment.
The combined use of BC and PRF had a significant effect on bone augmentation and this treatment exhibited promising clinical results for correcting posterior Seibert Class I ridge defects. The morphological classification of the reconstructive effect in this study can be utilized in future clinical work.
经典引导骨再生(GBR)治疗可为牙槽嵴缺损提供良好的临床效果。然而,在后牙区非美学区域,对于轻微的牙槽嵴缺损,广泛的骨增量是不必要的。因此,本研究使用胶原和富血小板纤维蛋白(PRF)混合物对轻微的后牙牙槽嵴缺损进行骨增量,并评估其效果。
22 例 Seibert Ⅰ类牙槽嵴缺损采用 BC 并用 PRF 膜覆盖(简化引导骨再生,简化 GBR)治疗,另 22 例采用 Bio-Oss 并用 Bio-Gide 覆盖(经典 GBR)治疗。术后 6 个月行锥形束 CT 成像,比较牙槽嵴的水平宽度(HW)和颊侧牙槽嵴的水平宽度,以评估成骨效果。此外,研究并分类颊侧牙槽嵴轮廓形态。
简化 GBR 的颊侧牙槽嵴轮廓 A 型 14 例,B 型 7 例,C 型 1 例;经典 GBR 的颊侧牙槽嵴轮廓 A 型 11 例,B 型 8 例,C 型 3 例。简化 GBR 治疗后 HW 平均增加 1.50mm,经典 GBR 治疗后增加 1.83mm。
BC 和 PRF 的联合使用对骨增量有显著效果,这种治疗方法对纠正后牙 Seibert Ⅰ类牙槽嵴缺损具有良好的临床效果。本研究中重建效果的形态学分类可用于未来的临床工作。