Economist Impact, London, UK.
Department of Medicine, Division of Haematology, Medical Oncology & Haematopoietic Stem Cell Transplantation, The University of Hong Kong, Hong Kong, Hong Kong.
BMC Public Health. 2024 Nov 21;24(1):3239. doi: 10.1186/s12889-024-20652-0.
The recent World Health Organization (WHO) resolution on oral health urges pivoting to a preventive approach and integration of oral health into the non-communicable diseases agenda. This study aimed to: 1) explore the healthcare costs of managing dental caries between the ages of 12 and 65 years across socioeconomic groups in six countries (Brazil, France, Germany, Indonesia, Italy, UK), and 2) estimate the potential reduction in direct costs from non-targeted and targeted oral health-promoting interventions.
A cohort simulation model was developed to estimate the direct costs of dental caries over time for different socioeconomic groups. National-level DMFT (dentine threshold) data, the relative likelihood of receiving an intervention (such as a restorative procedure, tooth extraction and replacement), and clinically-guided assumptions were used to populate the model. A hypothetical group of upstream and downstream preventive interventions were applied either uniformly across all deprivation groups to reduce caries progression rates by 30% or in a levelled-up fashion with the greatest gains seen in the most deprived group.
The population level direct costs of caries from 12 to 65 years of age varied between US10.2 billion in Italy to US$36.2 billion in Brazil. The highest per-person costs were in the UK at US$22,910 and the lowest in Indonesia at US$7,414. The per-person direct costs were highest in the most deprived group across Brazil, France, Italy and the UK. With the uniform application of preventive measures across all deprivation groups, the greatest reduction in per-person costs for caries management was seen in the most deprived group across all countries except Indonesia. With a levelling-up approach, cost reductions in the most deprived group ranged from US$3,948 in Indonesia to US$17,728 in the UK.
Our exploratory analysis shows the disproportionate economic burden of caries in the most deprived groups and highlights the significant opportunity to reduce direct costs via levelling-up preventive measures. The healthcare burden stems from a higher baseline caries experience and greater annual progression rates in the most deprived. Therefore, preventive measures should be start early, with a focus on lowering early childhood caries and continue through the life course.
最近世界卫生组织(WHO)关于口腔健康的决议敦促将重点转向预防方法,并将口腔健康纳入非传染性疾病议程。本研究旨在:1)探索六个国家(巴西、法国、德国、印度尼西亚、意大利和英国)不同社会经济群体中 12 至 65 岁人群管理龋齿的医疗保健成本;2)估计非针对性和针对性促进口腔健康干预措施可降低直接成本的潜力。
开发了一个队列模拟模型,以随着时间的推移估算不同社会经济群体的龋齿直接成本。使用国家级 DMFT(牙本质阈值)数据、接受干预的相对可能性(例如修复程序、拔牙和替换)以及临床指导假设来填充模型。一组假设的上游和下游预防干预措施均匀应用于所有贫困群体,将龋齿进展率降低 30%,或者以平衡的方式应用于最贫困群体,使最贫困群体获得最大收益。
12 至 65 岁人群的龋齿人群水平直接成本从意大利的 102 亿美元到巴西的 3620 亿美元不等。人均成本最高的是英国,为 22910 美元,最低的是印度尼西亚,为 7414 美元。在巴西、法国、意大利和英国,最贫困群体的人均直接成本最高。在所有国家(印度尼西亚除外),通过在所有贫困群体中均匀应用预防措施,在最贫困群体中管理龋齿的人均成本降低幅度最大。采用平衡方法,最贫困群体的成本降低幅度从印度尼西亚的 3948 美元到英国的 17728 美元不等。
我们的探索性分析表明,龋齿在最贫困群体中造成了不成比例的经济负担,并强调了通过平衡提升预防措施来降低直接成本的巨大机会。医疗保健负担源于最贫困群体的基线龋齿发生率更高和每年进展率更高。因此,预防措施应尽早开始,重点是降低幼儿龋齿的发病率,并贯穿整个生命周期。