Department of Urology, Weill Cornell Medical College-New York Presbyterian, New York, New York, USA,
Department of Urology, Weill Cornell Medical College-New York Presbyterian, New York, New York, USA.
Urol Int. 2022;106(7):664-671. doi: 10.1159/000522646. Epub 2022 Mar 23.
Knowledge gaps regarding available treatment and social stigmatization are barriers to care in patients with overactive bladder (OAB). We assessed the feasibility of an OAB education program targeting older community-dwelling females.
Community-dwelling women over 55 years old were recruited. Eligible participants underwent an education program covering continence-promotion strategies. The Overactive Bladder Questionnaire-Short Form and Short Form-12 were completed at baseline, 1 week, 3 months, and 6 months post-intervention to measure symptom bother and condition-specific and general quality of life (QoL). Data were analyzed using a linear mixed-effects model for repeated measures.
Thirty-seven female patients with OAB symptoms at baseline were assessed with the majority from Latino/Hispanic or Black/African American ethnic/racial backgrounds. For our youngest subgroup (≤68 years old), significant improvements were observed at 3 and 6 months compared to 1 week post-intervention for symptom bother (3 months, -22.75, p = 0.006; 6 months, -25.76; p = 0.001) and condition-specific and health-related QoL subscale scores for concern (3 months, +23.76, p = 0.006; 6 months, +22.15, p = 0.011) and social interaction (3 months, +21.11, p = 0.017; 6 months, +20.51; p = 0.021). For all age subgroups, improvements in general QoL measures for mental health were seen at 3 and 6 months compared to baseline (3 months, +7.57, p = 0.02; 6 months, +6.70; p = 0.048).
Statistically significant improvements in symptom bother, condition-specific, and general QoL measures were observed following an OAB education program pilot study in a predominantly minority female population. Further studies are needed to support efficacy and optimize program design.
对现有治疗方法的知识差距和社会污名化是影响过度膀胱（OAB）患者获得治疗的障碍。我们评估了针对老年社区女性的 OAB 教育计划的可行性。
招募 55 岁以上的社区居住女性。符合条件的参与者接受了涵盖促进控尿策略的教育计划。在干预后 1 周、3 个月和 6 个月时，使用过度膀胱问卷-短表和简明健康状况量表完成简短形式，以测量症状困扰以及特定疾病和一般生活质量（QoL）。使用重复测量的线性混合效应模型分析数据。
在基线时，有 37 名有 OAB 症状的女性患者接受了评估，大多数患者来自拉丁裔/西班牙裔或黑人/非裔美国人的种族背景。对于我们年龄最小的亚组（≤68 岁），与干预后 1 周相比，在 3 个月和 6 个月时，症状困扰（3 个月，-22.75，p=0.006；6 个月，-25.76；p=0.001）以及特定疾病和健康相关 QoL 子量表评分的关注（3 个月，+23.76，p=0.006；6 个月，+22.15，p=0.011）和社会互动（3 个月，+21.11，p=0.017；6 个月，+20.51；p=0.021）有显著改善。对于所有年龄亚组，与基线相比，在 3 个月和 6 个月时，心理健康的一般 QoL 测量均有改善（3 个月，+7.57，p=0.02；6 个月，+6.70；p=0.048）。
在以少数民族女性为主的人群中进行 OAB 教育计划试点研究后，观察到症状困扰、特定疾病和一般 QoL 测量的统计学显著改善。需要进一步的研究来支持疗效并优化计划设计。
