ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, School of Dentistry, University Complutense of Madrid (UCM), Madrid, Spain.
Dental Clinic, School of Dentistry, Albanian University, Tirana, Albania.
BMC Oral Health. 2022 Mar 23;22(1):89. doi: 10.1186/s12903-022-02121-5.
The objective was to qualitatively and quantitatively describe the subgingival cultivable bacteria in Albanian subjects and to compare it with a similar Spanish population.
Consecutive patients, diagnosed as periodontitis in stages I-II or III-IV, and as periodontally healthy or with gingivitis, were studied clinically and microbiologically by means of microbiological culture, including total anaerobic counts, proportions, and frequency of detection of target species. Outcome variables were analysed by Mann-Whitney, Kruskal-Wallis, ANOVA, ANCOVA and Chi-square tests.
In this cross-sectional study, 83 (Albania) and 90 (Spain) subjects were included. No statistically significant differences were observed between test and control populations regarding demographic variables or smoking habit. Significantly higher total anaerobic counts in the Albanian population (p = 0.022) were observed, especially in the periodontal health/gingivitis group (p = 0.001). In the test population, the proportions of the cultivable bacteria of Fusobacterium nucleatum were significantly lower in both the healthy/gingivitis (p = 0.022) and stages I-II periodontitis (p = 0.034) groups.
The subgingival cultivable bacteria in both periodontitis and non-periodontitis subjects from Albania showed significantly higher total anaerobic counts and lower proportions of the cultivable bacteria of F. nucleatum than a similar population of subjects from Spain.
本研究旨在定性和定量描述阿尔巴尼亚人群的龈下可培养细菌，并将其与类似的西班牙人群进行比较。
连续的患者，被诊断为牙周炎 I-II 期或 III-IV 期，以及牙周健康或牙龈炎，通过微生物培养进行临床和微生物学研究，包括总厌氧菌计数、目标物种的比例和检测频率。通过 Mann-Whitney、Kruskal-Wallis、ANOVA、ANCOVA 和卡方检验分析结果变量。
在这项横断面研究中，纳入了 83 名（阿尔巴尼亚）和 90 名（西班牙）受试者。在人口统计学变量或吸烟习惯方面，试验组和对照组之间没有观察到统计学上的显著差异。观察到阿尔巴尼亚人群的总厌氧菌计数显著升高（p=0.022），尤其是在牙周健康/牙龈炎组（p=0.001）。在试验组中，可培养的牙龈卟啉单胞菌的比例在健康/牙龈炎（p=0.022）和 I-II 期牙周炎（p=0.034）组中均显著降低。
与来自西班牙的类似人群相比，来自阿尔巴尼亚的牙周炎和非牙周炎患者的龈下可培养细菌的总厌氧菌计数显著升高，而可培养的牙龈卟啉单胞菌的比例较低。
