Ohara N, Kitamura N, Yamada J, Yamashita T
Res Vet Sci. 1986 Jul;41(1):21-7.
The gastroenteropancreatic (GEP) endocrine cells of the Japanese field vole were studied immunohistochemically. Somatostatin-, 5-hydroxytryptamine-, glicentin-, glucagon-, bovine pancreatic polypeptide-, gastrin-, gastric inhibitory polypeptide-, cholecystokinin-, substance P-, secretin-, neurotensin- and insulin-immunoreactive cells were revealed. The characteristic findings of the regional distribution and relative frequency of these immunoreactive cells in the GEP system of the vole were as follows. Somatostatin-immunoreactive cells were more numerous in the oxyntic glands than in the pyloric glands. Some somatostatin-immunoreactive cells were found in small clusters in the oxyntic glands. Gastrin-immunoreactive cells were detected not only in the pyloric glands and small intestine but also in the caecum and spiral colon. Gastric inhibitory polypeptide-immunoreactive cells were also detected in the pyloric glands and no motilin-immunoreactive cell was found in the gastroenteropancreatic system.
采用免疫组织化学方法对日本田鼠的胃肠胰（GEP）内分泌细胞进行了研究。发现了生长抑素、5-羟色胺、胰高血糖素样肽、胰高血糖素、牛胰多肽、胃泌素、胃抑制性多肽、胆囊收缩素、P物质、促胰液素、神经降压素和胰岛素免疫反应性细胞。田鼠GEP系统中这些免疫反应性细胞的区域分布和相对频率的特征性发现如下。胃底腺中生长抑素免疫反应性细胞比幽门腺中更多。在胃底腺中发现一些生长抑素免疫反应性细胞呈小簇状。胃泌素免疫反应性细胞不仅在幽门腺和小肠中检测到，在盲肠和螺旋结肠中也有检测到。胃抑制性多肽免疫反应性细胞也在幽门腺中检测到，而在胃肠胰系统中未发现胃动素免疫反应性细胞。
