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吸血蝙蝠(Desmodos rotundus)胃肠胰(GEP)内分泌细胞的免疫细胞化学研究。

Immunocytochemical study of gastro-entero-pancreatic (GEP) endocrine cells in the vampire bat (Desmodos rotundus).

作者信息

Yamada J, Campos V J, Kitamura N, Pacheco A C, Yamashita T, Caramaschi U

出版信息

Gegenbaurs Morphol Jahrb. 1984;130(6):845-56.

PMID:6152240
Abstract

The distribution and frequency of gastro-entero-pancreatic (GEP) endocrine cells were studied in vampire bats by immunocytochemistry. Moderate numbers of somatostatin- and a few 5-hydroxytryptamine (5-HT)- and glucagon-immunoreactive cells were seen in the fundic cecum of the stomach. Numerous gastrin- and moderate numbers of somatostatin- and 5-HT-immunoreactive cells were found in the pyloric region. Moderate numbers of 5-HT-, somatostatin-, and gastrin-immunoreactive cells also were found in BRUNNER's glands. In addition to the above-mentioned 4 immunoreactive cell types, cells immunoreactive for glicentin, secretin, cholecystokinin (CCK), gastric inhibitory peptide (GIP), and neurotensin were found in the intestine. Numerous insulin-, moderate numbers of somatostatin- and glucagon-, and a few 5-HT-immunoreactive cells were detected in the pancreatic islets with lesser numbers scattered within the exocrine pancreas. Motilin- and pancreatic polypeptide-immunoreactive cells were not observed in this study.

摘要

通过免疫细胞化学方法研究了吸血蝙蝠胃肠胰(GEP)内分泌细胞的分布和频率。在胃的盲囊部可见中等数量的生长抑素免疫反应性细胞以及少量5-羟色胺(5-HT)和胰高血糖素免疫反应性细胞。在幽门区发现大量胃泌素免疫反应性细胞以及中等数量的生长抑素和5-HT免疫反应性细胞。在布伦纳腺中也发现了中等数量的5-HT、生长抑素和胃泌素免疫反应性细胞。除上述4种免疫反应性细胞类型外,在肠道中还发现了对胰高血糖素样肽、促胰液素、胆囊收缩素(CCK)、胃抑制肽(GIP)和神经降压素呈免疫反应性的细胞。在胰岛中检测到大量胰岛素免疫反应性细胞、中等数量的生长抑素和胰高血糖素免疫反应性细胞以及少量5-HT免疫反应性细胞,在外分泌胰腺中也有少量散在分布。在本研究中未观察到胃动素和胰多肽免疫反应性细胞。

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引用本文的文献

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Anatomical study of the intestine of the insect-feeder bat, Myotis frater kaguae.食虫蝙蝠小伏翼卡瓜亚种肠道的解剖学研究。
J Anat. 1985 Oct;142:141-50.
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An immunohistochemical study of gastrointestinal endocrine cells in a nectarivorous marsupial, the honey possum (Tarsipes rostratus).对食蜜有袋动物蜜袋鼩(Tarsipes rostratus)胃肠道内分泌细胞的免疫组织化学研究。
J Anat. 1989 Feb;162:157-68.