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[改善脓毒症患者长期预后的康复策略]

[Rehabilitation strategy for the improvement of long-term outcomes of patients after sepsis].

作者信息

Yao Y M, Zhang H

机构信息

Translational Medicine Research Center, Medical Innovation Research Division and the Fourth Medical Center of PLA General Hospital, Beijing 100048, China.

出版信息

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Mar 20;38(3):201-206. doi: 10.3760/cma.j.cn501120-20211004-00344.

DOI:10.3760/cma.j.cn501120-20211004-00344
PMID:35325964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11705240/
Abstract

Survivors of sepsis still face high risks of secondary infection and mortality after hospital discharge. Meanwhile, the persistent cognitive, psychological, and physical disorders affect their long-term outcomes and life qualities. In the current review, we analyze the factors for the poor outcomes and discuss the beneficial rehabilitation strategies to improve the long-term outcomes of patients after sepsis, including psychological intervention, early mobility, nutrition support, and immune modulation, etc.

摘要

脓毒症幸存者在出院后仍面临继发感染和死亡的高风险。同时，持续存在的认知、心理和身体障碍会影响他们的长期预后和生活质量。在本综述中，我们分析了导致不良预后的因素，并探讨了有益的康复策略，以改善脓毒症患者的长期预后，包括心理干预、早期活动、营养支持和免疫调节等。

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本文引用的文献

1
[Deepening the understanding of the diagnostic system and therapeutic strategy for burn sepsis].[深化对烧伤脓毒症诊断系统和治疗策略的理解]
Zhonghua Shao Shang Za Zhi. 2021 May 20;37(5):404-409. doi: 10.3760/cma.j.cn501120-20200703-00337.
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Over 20 years of ICU diary research 1999-2020.1999年至2020年超过20年的重症监护病房日记研究。
Intensive Crit Care Nurs. 2021 Jun;64:102961. doi: 10.1016/j.iccn.2020.102961. Epub 2021 Mar 6.
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Crit Care Med. 2020 Sep;48(9):1271-1279. doi: 10.1097/CCM.0000000000004443.
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5
Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study.全球、地区和国家脓毒症发病率和死亡率，1990-2017 年：全球疾病负担研究分析。
Lancet. 2020 Jan 18;395(10219):200-211. doi: 10.1016/S0140-6736(19)32989-7.
6
The Role of Opioid Receptors in Immune System Function.阿片受体在免疫系统功能中的作用。
Front Immunol. 2019 Dec 20;10:2904. doi: 10.3389/fimmu.2019.02904. eCollection 2019.
7
Post-sepsis syndrome - an evolving entity that afflicts survivors of sepsis.败血症后综合征——一种困扰败血症幸存者的不断演变的实体。
Mol Med. 2019 Dec 31;26(1):6. doi: 10.1186/s10020-019-0132-z.
8
ICU rehabilitation is associated with reduced long-term mortality from sepsis in patients with low skeletal muscle mass: a case control study.ICU康复与骨骼肌质量低的脓毒症患者长期死亡率降低相关：一项病例对照研究。
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Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation.谷氨酰胺：代谢与免疫功能、补充与临床转化。
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