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COVID-19 恢复期的基质和内皮单纯疱疹病毒角膜炎再激活 - 一例报告。

Stromal and endothelial herpes simplex virus keratitis reactivation in the convalescent period of COVID-19 - A case report.

机构信息

Department of Cornea and External Disease, Disha Eye Hospitals, Barrackpore, Kolkata, West Bengal, India.

Department of Oculoplasty and Orbit, Disha Eye Hospitals, Barrackpore, Kolkata, West Bengal, India.

出版信息

Indian J Ophthalmol. 2022 Apr;70(4):1410-1412. doi: 10.4103/ijo.IJO_2838_21.

Abstract

A 73-year-old lady presented with a white spot and redness in the left eye for 1 month and had been treated elsewhere as a case of fungal keratitis. She had severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral infection 2 months before. Her past ocular history and examination gave a probable diagnosis of herpetic stromal and endothelial keratitis. She responded to oral acyclovir and topical steroid, leading to resolution of stromal edema and inflammation. Anterior chamber fluid polymerase chain reaction (PCR) confirmed pathogen herpes simplex virus (HSV)-1. HSV ocular reactivation after coronavirus disease 2019 (COVID-19) has been reported currently. The present report will add knowledge about this potential opportunistic ophthalmic infection during the recovery phase of COVID-19 disease.

摘要

一位 73 岁的女士左眼出现白点和发红,持续了 1 个月,并在其他地方被诊断为真菌性角膜炎。她在 2 个月前患有严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)病毒感染。她的既往眼部病史和检查提示可能为疱疹性基质和内皮层角膜炎。她对口服阿昔洛韦和局部类固醇治疗有反应,导致基质水肿和炎症消退。前房液聚合酶链反应(PCR)证实病原体为单纯疱疹病毒(HSV)-1。目前已有报道称 COVID-19 后 HSV 眼复发。本报告将增加关于 COVID-19 疾病恢复期这种潜在机会性眼部感染的知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9fd/9240579/0e6b4fd5dcb6/IJO-70-1410-g001.jpg

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