Rupe Cosimo, Basco Alessia, Schiavelli Anna, Cassano Alessandra, Micciche' Francesco, Galli Jacopo, Cordaro Massimo, Lajolo Carlo
Head and Neck Department, Fondazione Policlinico Universitario A. Gemelli-IRCCS, School of Dentistry, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168 Rome, Italy.
Department of Medical Oncology, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Institute of Radiology, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168 Rome, Italy.
Cancers (Basel). 2022 Mar 10;14(6):1411. doi: 10.3390/cancers14061411.
(1) Background: The general hypothesis that HNC patients show compromised oral health (OH) is generally accepted, but it is not evidence-based. The objective of this baseline report of a prospective observational study was to describe the oral health of a cohort of patients with HNC at the time of dental evaluation prior to radiotherapy (RT). (2) Materials and Methods: Two hundred and thirteen patients affected by HNC who had received an indication for RT were examined with the support of orthopantomography (OPT). The DMFt of all included subjects, their periodontal status and the grade of mouth opening were recorded. (3) Results: A total of 195 patients were ultimately included: 146/195 patients (74.9%) showed poor OH (defined as having a DMFt score ≥ 13 and severe periodontitis). The following clinical characteristics were correlated with poor oral health in the univariate analysis: tumor site, smoking habit and age of the patients (in decades); χ2 test, p < 0.05. (4) Conclusions: This study confirms that the OH of HNC patients is often compromised even before the beginning of cancer treatment and, consequently, highlights how important it is to promptly schedule a dental evaluation at the moment of diagnosis of the cancer.
(1) 背景：头颈部癌症（HNC）患者口腔健康受损这一普遍假设已被广泛接受，但缺乏循证依据。这项前瞻性观察研究基线报告的目的是描述一组HNC患者在放疗（RT）前进行牙科评估时的口腔健康状况。(2) 材料与方法：在曲面体层摄影（OPT）的辅助下，对213例接受RT指征的HNC患者进行了检查。记录所有纳入受试者的龋失补牙数（DMFt）、牙周状况和张口度。(3) 结果：最终共纳入195例患者：195例患者中有146例（74.9%）口腔健康状况较差（定义为DMFt评分≥13且患有重度牙周炎）。在单因素分析中，以下临床特征与口腔健康状况较差相关：肿瘤部位、吸烟习惯和患者年龄（以十岁为单位）；卡方检验，p<0.05。(4) 结论：本研究证实，HNC患者的口腔健康即使在癌症治疗开始前也常常受损，因此，凸显了在癌症诊断时及时安排牙科评估的重要性。
