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使用具有较大前后径的人工瓣膜环修复严重瓣环扩张且瓣叶组织丰富的二尖瓣。

Repair of Mitral Valves with Severe Annular Dilatation and Abundant Leaflet Tissue Using a Prosthetic Ring with a Large Anterior-Posterior Diameter.

作者信息

Sideris Konstantinos, Burri Melchior, Bordne Joanna, Vitanova Keti, Voss Bernhard, Krane Markus, Lange Rüdiger

机构信息

Department of Cardiovascular Surgery, German Heart Centre Munich, Technische Universität München, 80636 Munich, Germany.

Insure (Institute for Translational Cardiac Surgery), Department of Cardiovascular Surgery, German Heart Centre Munich, Technische Universität München, 80636 Munich, Germany.

出版信息

J Clin Med. 2022 Mar 19;11(6):1709. doi: 10.3390/jcm11061709.

Abstract

BACKROUND

Mitral valve (MV) repair in the case of a large anterior-posterior diameter and redundant valve tissue remains challenging and favors repair with a ring that exhibits a large anterior-posterior diameter. Compared to other available rings, the Medtronic Simulus annuloplasty ring shows the largest anterior-posterior diameter. This study reports for the first time mid-term results using this annuloplasty ring.

METHODS

Between 11/2015 and 12/2019, a total of 378 patients underwent MV repair for degenerative mitral regurgitation using the Medtronic Simulus ring, according to the following selection criteria: large MV annuli, abundant leaflet tissue (i.e., Barlow disease), and risk for SAM.

RESULTS

Overall survival after 5 years was 90.8 ± 4.6%. Five patients required valve-related reoperations because of ring dehiscence ( = 1), progression of native valve disease ( = 2), dehiscence of quadrangular resection suture ( = 1), and endocarditis ( = 1). The cumulative incidence of valve-related reoperation at 5 years was 1.3 ± 0.5%. At latest follow-up, echocardiography demonstrated excellent valve function with no/mild MR in 299 patients (94.6%). Two patients (0.6%) had more than moderate MR. No patient developed SAM after repair.

CONCLUSION

Repair of MV with large annuli and abundant leaflet tissue with the Medtronic Simulus annuloplasty ring shows excellent mid-term results regarding reoperation rates and recurrent MR.

摘要

背景

对于前后径较大且瓣膜组织冗余的二尖瓣(MV)修复仍然具有挑战性,使用前后径较大的环进行修复更为有利。与其他可用的环相比,美敦力Simulus瓣环成形环的前后径最大。本研究首次报告了使用该瓣环成形环的中期结果。

方法

在2015年11月至2019年12月期间,共有378例患者根据以下选择标准使用美敦力Simulus环进行退行性二尖瓣反流的MV修复:MV瓣环大、瓣叶组织丰富(即巴洛病)和发生SAM的风险。

结果

5年后的总生存率为90.8±4.6%。5例患者因瓣环裂开(n = 1)、原生瓣膜疾病进展(n = 2)、四边形切除缝线裂开(n = 1)和心内膜炎(n = 1)需要进行瓣膜相关再次手术。5年时瓣膜相关再次手术的累积发生率为1.3±0.5%。在最近一次随访时,超声心动图显示299例患者(94.6%)瓣膜功能良好,无/轻度二尖瓣反流。2例患者(0.6%)有中度以上二尖瓣反流。修复后无患者发生SAM。

结论

使用美敦力Simulus瓣环成形环对瓣环大且瓣叶组织丰富的MV进行修复,在再次手术率和复发性二尖瓣反流方面显示出优异的中期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a261/8955655/6437e87a7c39/jcm-11-01709-g003.jpg

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