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炎症性肠病患儿的代谢性骨病

Metabolic Bone Disorders in Children with Inflammatory Bowel Diseases.

作者信息

Olczyk Mariusz, Czkwianianc Elżbieta, Socha-Banasiak Anna

机构信息

Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Pomorska 251, 92-216 Lodz, Poland.

Department of Gastroenterology, Allergology and Pediatrics, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.

出版信息

Life (Basel). 2022 Mar 15;12(3):423. doi: 10.3390/life12030423.

Abstract

In recent years, there has been a noticeable increase in the incidence of inflammatory bowel diseases in the pediatric population. Entry observations demonstrate anemia, malabsorption, deficiencies in vitamin D and calcium. These aspects, together with the systemic action of pro-inflammatory cytokines and steroid therapy are widely recognized as factors influencing bone metabolism. Presently, however, there are very few studies that can be found in the scientific literature on metabolic disorders in patients with IBD, especially in the pediatric population as the coexistence has not been sufficiently examined and understood. This review aims to summarize the currently available literature, as well as assess which areas have information gaps and need further research.

摘要

近年来,儿科人群中炎症性肠病的发病率显著上升。入院观察显示有贫血、吸收不良、维生素D和钙缺乏。这些方面,连同促炎细胞因子的全身作用和类固醇治疗,被广泛认为是影响骨代谢的因素。然而,目前在科学文献中很少能找到关于炎症性肠病患者代谢紊乱的研究,尤其是儿科人群,因为两者并存的情况尚未得到充分研究和理解。本综述旨在总结当前可用的文献,并评估哪些领域存在信息空白以及需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7198/8954892/8457295f0f4c/life-12-00423-g001.jpg

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