Department of Biotechnology, Sri Padmavati Mahila Visvavidyalayam, Tirupati, Andhra Pradesh, 517 502, India; Dr. Buddolla's Institute of Life Sciences, Tirupati, 517502, Andhra Pradesh, India.
DST Purse Centre, Sri Venkateswara University, Tirupati, Andhra Pradesh, India.
Clin Nutr ESPEN. 2022 Apr;48:5-16. doi: 10.1016/j.clnesp.2022.02.017. Epub 2022 Feb 22.
Studies have extensively investigated a variety of health benefits associated with probiotic supplements, which often contain live microorganisms. The effect of probiotic supplements on cancer prevention and on chemotherapy effectiveness and toxicity are major areas that researchers have focused on. Recently, several researchers have concentrated on assessing the efficacy of probiotics in the treatment of cervical cancer, a leading malignancy in gynecology worldwide, especially in developing countries. To date, numerous clinical studies have demonstrated the efficacy of probiotics in preventing cervical cancer, but their dosages, bacterial strains, and duration of therapy are somewhat inconsistent. In this review, we have systematically updated the role of probiotics in cervical cancer management.
研究已经广泛研究了与益生菌补充剂相关的多种健康益处,这些补充剂通常含有活菌。益生菌补充剂对癌症预防以及化疗效果和毒性的影响是研究人员关注的主要领域。最近,一些研究人员专注于评估益生菌在治疗宫颈癌方面的功效,宫颈癌是全球妇科中的主要恶性肿瘤,尤其是在发展中国家。迄今为止,许多临床研究已经证明了益生菌在预防宫颈癌方面的功效,但它们的剂量、细菌菌株和治疗时间有些不一致。在这篇综述中,我们系统地更新了益生菌在宫颈癌管理中的作用。