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血清素能传递增强后抗利尿激素的释放并非由于外周肾素-血管紧张素系统的激活。

Vasopressin release after enhanced serotonergic transmission is not due to activation of the peripheral renin-angiotensin system.

作者信息

Steardo L, Iovino M

出版信息

Brain Res. 1986 Sep 10;382(1):145-8. doi: 10.1016/0006-8993(86)90122-8.

DOI:10.1016/0006-8993(86)90122-8
PMID:3533208
Abstract

Pharmacological enhancement of 5-hydroxytryptamine (5-HT) transmission increases plasma vasopressin in rats. To investigate whether this effect is mediated through activation of the peripheral renin-angiotensin system, plasma vasopressin concentrations were measured after 5-HT activation in rats with lesions of the subfornical organ or pretreated with saralasin. The results show that the 5-HT-induced elevation of vasopressin is not due to activation of the peripheral renin-angiotensin system.

摘要

5-羟色胺（5-HT）传递的药理学增强会增加大鼠血浆中的血管加压素。为了研究这种作用是否通过外周肾素-血管紧张素系统的激活介导，在穹窿下器官损伤的大鼠或用沙拉新预处理的大鼠中，在5-HT激活后测量血浆血管加压素浓度。结果表明，5-HT诱导的血管加压素升高并非由于外周肾素-血管紧张素系统的激活。

相似文献

1
Vasopressin release after enhanced serotonergic transmission is not due to activation of the peripheral renin-angiotensin system.血清素能传递增强后抗利尿激素的释放并非由于外周肾素-血管紧张素系统的激活。
Brain Res. 1986 Sep 10;382(1):145-8. doi: 10.1016/0006-8993(86)90122-8.
2
Effect of transection of subfornical organ efferent projections on vasopressin release induced by angiotensin or isoprenaline in the rat.
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Lateral hypothalamic region excites the activity of vasopressin neurons in the supraoptic nucleus through subfornical organ neurons.
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Thirst and vasopressin secretion following central administration of angiotensin II in rats with lesions of the septal area and subfornical organ.在患有隔区和穹窿下器官损伤的大鼠中，中枢给予血管紧张素II后的口渴和抗利尿激素分泌。
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Role for the subfornical organ in vasopressin release.穹窿下器在血管加压素释放中的作用。
Brain Res Bull. 1984 Jul;13(1):43-7. doi: 10.1016/0361-9230(84)90006-6.
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Electrical stimulation in subfornical organ increases plasma vasopressin concentrations in the conscious rat.穹窿下器官的电刺激会增加清醒大鼠的血浆血管加压素浓度。
Am J Physiol. 1986 Aug;251(2 Pt 2):R425-8. doi: 10.1152/ajpregu.1986.251.2.R425.
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Pharmacological evidence for a role of brain serotonin in the maintenance of plasma renin activity in unanesthetized rats.脑5-羟色胺在维持未麻醉大鼠血浆肾素活性中作用的药理学证据。
J Pharmacol Exp Ther. 1981 Oct;219(1):85-90.
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Vasopressin release to central and peripheral angiotensin II in rats with lesions of the subfornical organ.穹窿下器损伤大鼠中血管加压素对中枢和外周血管紧张素II的释放
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Vasopressin release induced by intracranial injection of eledoisin is mediated by central angiotensin II.颅内注射eledoisin诱导的血管加压素释放是由中枢血管紧张素II介导的。
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Role of the renin-angiotensin system in isoprenaline-induced vasopressin release.肾素-血管紧张素系统在异丙肾上腺素诱导的血管加压素释放中的作用。
J Cardiovasc Pharmacol. 1980 Nov-Dec;2(6):815-24. doi: 10.1097/00005344-198011000-00010.

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Metergoline, naloxone, and sodium valproate did not modify arginine vasopressin response to insulin-induced hypoglycemia in man.麦角苄酯、纳洛酮和丙戊酸钠不会改变人体中精氨酸加压素对胰岛素诱导的低血糖的反应。
J Endocrinol Invest. 1988 May;11(5):365-9. doi: 10.1007/BF03349056.
3
Central administration of 5-HT activates 5-HT1A receptors to cause sympathoexcitation and 5-HT2/5-HT1C receptors to release vasopressin in anaesthetized rats.
在麻醉大鼠中，中枢给予5-羟色胺可激活5-羟色胺1A受体导致交感神经兴奋，并激活5-羟色胺2/5-羟色胺1C受体释放血管加压素。
Br J Pharmacol. 1992 Dec;107(4):1020-8. doi: 10.1111/j.1476-5381.1992.tb13401.x.
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Effect of m-chlorophenylpiperazine on plasma arginine-vasopressin concentrations in healthy subjects.
Psychopharmacology (Berl). 1992;108(1-2):225-8. doi: 10.1007/BF02245312.