Department of Internal medicine, Division of Chest Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Department of Surgery, Division of Neurosurgery, Dalin Tzu Chi Hospital, Chia-Yi, Taiwan and school of medicine, Tzuchi University, Hualien, Taiwan.
Am J Hosp Palliat Care. 2022 Nov;39(11):1342-1349. doi: 10.1177/10499091221074636. Epub 2022 Mar 25.
Factors related to the end-of-life decisions of patients with intracranial hemorrhage who were successfully weaned from prolonged mechanical ventilation remain unclear. This study aimed to evaluate factors that influence the end-of-life decisions of these patients.
This retrospective study examined patients with intracranial hemorrhage successfully weaned from prolonged mechanical ventilation between January 2012 and December 2017. The following data was collected and analyzed: age, gender, comorbidities, Glasgow Coma Scale scores, receipt or non-receipt of intracranial hemorrhage surgery, discharge status, and end-of-life decisions.
In total, 91 patients with intracranial hemorrhage were successfully weaned from prolonged mechanical ventilation. The families of 62 (68.1%) patients signed the do-not-resuscitate order. A Glasgow Coma Scale score of ≥10 at discharge from the respiratory care center and zero comorbidities were the influencing factors between patients whose do-not-resuscitate orders were signed and those whose orders were not signed. Patients with intracranial hemorrhage successfully weaned from prolonged mechanical ventilation had chronic kidney disease comorbidity and Glasgow Coma Scale score of <7 on admission to respiratory care center with a general ward mortality rate of 83.3%.
The families of intracranial hemorrhage patients with multiple comorbidities and higher neurologic impairment after successful weaning from the ventilator believed that palliative therapy would provide a greater benefit. Patients with intracranial hemorrhage successfully weaned from prolonged mechanical ventilation with chronic kidney disease comorbidity and Glasgow Coma Scale score of <7 on admission to respiratory care center are candidates for the consideration of hospice care with ventilator withdrawal.
评估影响此类患者临终决策的因素。
本回顾性研究纳入了 2012 年 1 月至 2017 年 12 月期间成功撤机的颅内出血患者。收集并分析以下数据:年龄、性别、合并症、格拉斯哥昏迷评分、是否接受颅内出血手术、出院状态和临终决策。
共有 91 例颅内出血患者成功撤机。62 例(68.1%)患者家属签署了不复苏医嘱。呼吸治疗中心出院时格拉斯哥昏迷评分≥10 分和无合并症是签署与未签署不复苏医嘱患者的影响因素。成功撤机的颅内出血患者合并慢性肾脏病且入呼吸治疗中心时格拉斯哥昏迷评分<7,普通病房死亡率为 83.3%。
对于成功撤机的合并多种合并症和神经功能损伤较大的颅内出血患者,其家属认为姑息治疗会带来更大的获益。对于合并慢性肾脏病且入呼吸治疗中心时格拉斯哥昏迷评分<7 的成功撤机的颅内出血患者,应考虑进行临终关怀并撤机。