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螺旋通道中的粘弹性粒子聚焦与分离

Viscoelastic Particle Focusing and Separation in a Spiral Channel.

作者信息

Feng Haidong, Jafek Alexander R, Wang Bonan, Brady Hayden, Magda Jules J, Gale Bruce K

机构信息

Department of Mechanical Engineering, University of Utah, Salt Lake City, UT 84112, USA.

Department of Chemical Engineering, University of Utah, Salt Lake City, UT 84112, USA.

出版信息

Micromachines (Basel). 2022 Feb 25;13(3):361. doi: 10.3390/mi13030361.

Abstract

As one type of non-Newtonian fluid, viscoelastic fluids exhibit unique properties that contribute to particle lateral migration in confined microfluidic channels, leading to opportunities for particle manipulation and separation. In this paper, particle focusing in viscoelastic flow is studied in a wide range of polyethylene glycol (PEO) concentrations in aqueous solutions. Polystyrene beads with diameters from 3 to 20 μm are tested, and the variation of particle focusing position is explained by the coeffects of inertial flow, viscoelastic flow, and Dean flow. We showed that particle focusing position can be predicted by analyzing the force balance in the microchannel, and that particle separation resolution can be improved in viscoelastic flows.

摘要

作为一种非牛顿流体,粘弹性流体具有独特的性质,有助于颗粒在受限微流控通道中的横向迁移,从而为颗粒操控和分离提供了机会。本文研究了水溶液中不同聚乙二醇(PEO)浓度下粘弹性流中的颗粒聚焦现象。测试了直径为3至20μm的聚苯乙烯珠,并通过惯性流、粘弹性流和迪恩流的共同作用解释了颗粒聚焦位置的变化。我们表明,通过分析微通道中的力平衡可以预测颗粒聚焦位置,并且在粘弹性流中可以提高颗粒分离分辨率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a93/8954746/6f8955d987cf/micromachines-13-00361-g001.jpg

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