Department of Infectious Diseases and Hepatology, Medical University of Białystok, 15-540 Białystok, Poland.
Department of Infectious Diseases, Jan Kochanowski University, 25-317 Kielce, Poland.
Viruses. 2022 Feb 26;14(3):482. doi: 10.3390/v14030482.
In 2016, the WHO announced a plan to eliminate viral hepatitis as a public health threat by 2030. In this narrative review, experts from Bulgaria, Croatia, the Czech Republic, Hungary, Latvia, Lithuania, Poland and Slovakia assessed the feasibility of achieving the WHO 2030 target for HCV infections in Central Europe. They focused mainly on HCV micro-elimination in prisons, where the highest incidence of HCV infections is usually observed, and the impact of the COVID-19 pandemic on the detection and treatment of HCV infections. According to the presented estimates, almost 400,000 people remain infected with HCV in the analyzed countries. Interferon-free therapies are available ad libitum, but the number of patients treated annually in the last two years has halved compared to 2017-2019, mainly due to the COVID-19 pandemic. None of the countries analyzed had implemented a national HCV screening program or a prison screening program. The main reason is a lack of will at governmental and prison levels. None of the countries analyzed see any chance of meeting the WHO targets for removing viral hepatitis from the public threat list by 2030, unless barriers such as a lack of political will and a lack of screening programs are removed quickly.
2016 年,世界卫生组织宣布了一项计划,旨在到 2030 年消除病毒性肝炎这一公共卫生威胁。在这篇叙述性评论中,来自保加利亚、克罗地亚、捷克共和国、匈牙利、拉脱维亚、立陶宛、波兰和斯洛伐克的专家评估了在中欧实现世界卫生组织 2030 年丙型肝炎病毒感染目标的可行性。他们主要关注监狱中的丙型肝炎病毒微消除,因为监狱通常是丙型肝炎病毒感染发生率最高的地方,以及 COVID-19 大流行对丙型肝炎病毒感染检测和治疗的影响。根据提出的估计,在分析的国家中,仍有近 40 万人感染丙型肝炎病毒。无干扰素治疗可自由使用,但与 2017-2019 年相比,过去两年每年接受治疗的患者数量减少了一半,主要是由于 COVID-19 大流行。分析的国家中没有一个国家实施了国家丙型肝炎病毒筛查计划或监狱筛查计划。主要原因是政府和监狱层面缺乏意愿。分析的国家都认为,除非迅速消除缺乏政治意愿和缺乏筛查计划等障碍,否则在 2030 年之前将病毒性肝炎从公共威胁名单中消除的世界卫生组织目标无法实现。